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23 Cards in this Set

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1.     Fastest growing tumor
– Burkitt’s
2.     found in half of all autopsies
PE
3.     Courvoisier’s Law:
tumors that obstruct the common bile duct cause enlarged gallbladders, but obstructing gallstones do not (too much scarring), so if you can palpate the gallbladder you’e probably looking at cancer.
4.     Only DNA virus to replicate in cytoplasm:
Pox
5.     Only RNA virus to replicate in nucleus:
Influenza
6.     has the only protein capsule
Bacillus anthracis
7.     elicits lymphocytosis rather than granulocytosis
Bordetella pertussis (Whooping Cough)
8.     grow without destroying the normal architecture of the lung
Bronchioalveolar carcinomas
9.     often lacks a capsule and, when stained with GMS, looks just like Pneumycistis carinii, except that Cryptococcus lacks the prominent nucleoli.
Cryptococcus neoformans
10.   Weil Felix reaction:
(+)R. rickettssi & (+)Proteus vulgaris & P. mirabilis
11.   Treponema pallidum (Syphilis) tests:
1)VDRL 2)FTA-Abs: most widely used 3)TPI (immobilization test – most expensive but the Gold Standard)
Cytokine
Source
Function
IL 1
1.     Monocytes, macrophages
Stimulates T cell proliferation & IL2 produciton
IL 2
2.     Macrophages, T & NK cells
Stim prolif of B, T & NK cell
IL 3
3.     T cells
GF of tissue mast cells & hematopoietic stem cells
IL 4
4.     T cells
­ growth of B & T cells/ ­ HLA II Ags
IL 5
5.     T cells
Maturation of B à plasma cell
IL 6
6.     T cells, monocytes
Maturation of B & T cell/ (-) fibroblasts
IFN a
7.     B cells, macrophages
Antiviral activity
IFN b
8.     Fibroblasts
Antiviral activity
IFN gamma
9.     T & NK cells
Antiviral activity, (+) macrophages, ­ HLA II Ags
TNF a
10.   Macrophages, T & NK cells
T cell prolif, IL 2 prod, cytotoxicity
TNF b
11.   T cells
T cell prolif, IL 2 prod, cytotoxicity