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50 Cards in this Set
- Front
- Back
releasing and inhibiting factors |
HYPOTHALAMUS peptides targets anterior pituitary modifies anterior pituitary activity |
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growth hormone (GH) |
ANTERIOR PITUITARY peptide increases bone and muscle growth, increases cell turnover rate; metabolic, growth of skeletal muscle and long bones, determines final size |
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hypo secretion of GH as child |
pituitary dwarfism
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hyper secretion of GH as child |
gigantism
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hyper secretion of GH as adult |
acromegaly
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prolactin |
ANTERIOR PITUITARY peptide targets the mammary gland stimulates milk production |
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thyroid stimulating hormone (TSH) |
TROPIC ANTERIOR PITUITARY peptide targets the thyroid gland increases the synthesis and release of thyroid hormone (TH); influences growth and activity of thyroid gland |
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adrenocorticotropic hormone (ACTH) |
ANTERIOR PITUITARY peptide regulates endocrine activity of adrenal cortex; increases growth and secretory activity of adrenal cortex |
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luteinizing hormone (LH) |
GONADOTROPIC ANTERIOR PITUITARY peptide targets ovaries and testes causes ovulation and testosterone production |
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follicle stimulating hormone (FSH) |
GONADOTROPIC ANTERIOR PITUITARY peptide targets ovaries and testes causes follicle development in ovaries and spermatogenesis (sperm formation) in testes |
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hypo secretion of LH and FSH |
sterility
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hyper secretion of LH and FSH |
multiple births
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antidiuretic hormone (ADH, vasopressin) |
POSTERIOR PITUITARY peptide targets kidneys causes kidneys to absorb more water, decreases urine output and increases blood volume; inhibits/prevents urine production |
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inhibition of ADH |
alcohol inhibits antidiuretic hormone; leads to dehydration and increased urine output |
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hypo secretion of ADH |
diabetes insipidus |
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oxytocin |
POSTERIOR PITUITARY peptide targets the breast and uterus causes milk production and uterine contractions |
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pitocin |
synthetic form of oxytocin used to induce or speed up labor |
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thyroid hormone (TH, thyroxine) |
THYROID modified amino acid made of 2 hormones: thyroxine and triiodothyronine major metabolic hormone, controls rate glucose is converted, important in normal growth and development, targets every cell |
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thyroid hormone in children |
necessary for physical and mental development |
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thyroid hormone in adults |
increases metabolic rate and temperature |
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goiter |
thyroid hormone requires iodine from diet, if not enough iodine goiter forms |
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hypo secretion of thyroid hormone in kids |
cretinism = dwarfism and metnal retardation |
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hypo secretion of thyroid hormone in adults |
myxedema = sluggishness, fatigue, obesity, low temperature |
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hyper secretion of thyroid hormone |
high metabolic rate, rapid heartbeat, heat intolerance, weight loss, agitation, bulging eyes |
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calcitonin |
THYROID, THYROID C CELLS peptide targets bone, kidney decreases calcium causes a decrease in blood calcium by causing calcium to be deposited into bones; released directly into blood in response to increasing levels of blood calcium production decreases w/ increasing age antagonist of parathyroid hormone |
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parathyroid hormone (PTH, parathormone) |
PARATHYROIDS peptide targets bone, kidney, small intestine increases calcium when calcium levels low, stimulates bone destruction to breakdown bone matrix and release calcium into blood; stimulates kidneys and intestines to absorb more calcium |
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hyper secretion of parathyroid hormone |
massive bone destruction, fragile bones, spontaneous fractures |
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thymosin |
THYMUS peptide *in children only* causes development of normal immune system and T cell development during childhood |
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epinephrine (adrenaline) and norepinephrine (noradrenaline) |
ADRENAL MEDULLA modified amino acid; catecholamine sympathetic stress response, rapid very similar in effects, only different in target receptors |
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cortisone and cortisol (glucocorticoids) |
ADRENAL CORTEX steroids promotes cellular metabolism and resists long term stressors and reduces inflammation and edema longer term stress response; increases blood glucose concentration; increases protein catabolism; decreases inflammation and immunity |
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aldosterone (mineralocorticoid) |
ADRENAL CORTEX targets kidneys increases sodium reabsorption to increase blood pressure regulates mineral and salt content of blood and water and electrolyte balance |
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sex steroids |
ADRENAL CORTEX androgen - male sex steroid estrogen - female sex steroid |
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adrenal tumor |
sex steroids can be overproduced and cause masculinization or feminization |
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hypo secretion of aldosterone |
addison's disease = bronze skin, H2O and sodium loss, weak muscles, shock |
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hyper secretion of aldosterone |
hyperaldosteronism = excessive water and sodium retention; elevated blood pressure and edema; loss of potassium that affects muscle and heart function |
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insulin |
PANCREAS (islets of Langerhans); B CELLS SECRETE peptide decreases blood glucose concentration; increases glycogen and fat storage released by pancreas when glucose high; when blood sugar levels drop, insulin release stops |
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type I diabetes |
body does not produce insulin, fixed with injections and pump |
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type 2 diabetes |
insulin receptors unable to respond, fixed with special diet and exercise and injections if needed |
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glucagon |
ENDOCRINE PANCREAS (Islets of Langerhans) ALPHA CELLS SECRETE peptide increases blood glucose concentration; decreases glycogen and fat storage antagonist of insulin targets liver to break down stored glycogen into glucose and release it into the blood |
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somatostatin (SS) |
PANCREAS (islets of Langerhans) D CELLS SECRETE peptide secreted by D-cells in the pyloric antrum and the duodenum inhibits many digestive processes |
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testosterone |
TESTES steroid promotes male sex characteristics; necessary for sperm production |
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hypo secretion of testosterone |
sterility |
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estrogen |
OVARIES / PLACENTA steroid promotes female sex characteristics; promotes menstrual cycle (endometrial growth) and development of breasts |
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progesterone |
OVARIES / PLACENTA steroid acts w/ estrogen to bring about menstrual cycle (endometrial secretion); keeps muscles of uterus quiet during pregnancy |
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atrial natriuretic factor (ANF) |
HEART peptide targets the kidneys increases urination to decrease blood pressure |
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erythropoietin |
KIDNEYS peptide targets bone marrow increases red blood cell production |
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melatonin |
PINEAL GLAND regulates sleep / wake and day / night cycles; coordinates fertility hormones; inhibits reproductive system development and sexual maturation before adult body size reached |
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relaxin* |
PLACENTA hormone that relaxes pelvic ligaments and pubic symphysis to widen the pelvis during delivery *not on mcat list |
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human placental lactogen (hPL)* |
PLACENTA works with estrogen and progesterone to prepare breasts for lactation *not on mcat list |
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human chorionic gonadotropin (hCG)* |
PLACENTA produced by developing embryo and fetal portion of placenta to continue estrogen and progesterone production keeps the uterine lining intact *not on mcat list |