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50 Cards in this Set

  • Front
  • Back

releasing and inhibiting factors

HYPOTHALAMUS


peptides


targets anterior pituitary


modifies anterior pituitary activity

growth hormone (GH)

ANTERIOR PITUITARY


peptide


increases bone and muscle growth, increases cell turnover rate; metabolic, growth of skeletal muscle and long bones, determines final size



hypo secretion of GH as child

pituitary dwarfism

hyper secretion of GH as child

gigantism

hyper secretion of GH as adult

acromegaly

prolactin

ANTERIOR PITUITARY


peptide


targets the mammary gland


stimulates milk production

thyroid stimulating hormone (TSH)

TROPIC ANTERIOR PITUITARY


peptide


targets the thyroid gland


increases the synthesis and release of thyroid hormone (TH); influences growth and activity of thyroid gland

adrenocorticotropic hormone (ACTH)

ANTERIOR PITUITARY


peptide


regulates endocrine activity of adrenal cortex; increases growth and secretory activity of adrenal cortex

luteinizing hormone (LH)

GONADOTROPIC ANTERIOR PITUITARY


peptide


targets ovaries and testes


causes ovulation and testosterone production



follicle stimulating hormone (FSH)

GONADOTROPIC ANTERIOR PITUITARY


peptide


targets ovaries and testes


causes follicle development in ovaries and spermatogenesis (sperm formation) in testes



hypo secretion of LH and FSH

sterility

hyper secretion of LH and FSH

multiple births

antidiuretic hormone (ADH, vasopressin)

POSTERIOR PITUITARY


peptide


targets kidneys


causes kidneys to absorb more water, decreases urine output and increases blood volume; inhibits/prevents urine production



inhibition of ADH

alcohol inhibits antidiuretic hormone; leads to dehydration and increased urine output

hypo secretion of ADH

diabetes insipidus

oxytocin

POSTERIOR PITUITARY


peptide


targets the breast and uterus


causes milk production and uterine contractions

pitocin

synthetic form of oxytocin used to induce or speed up labor

thyroid hormone (TH, thyroxine)

THYROID


modified amino acid


made of 2 hormones: thyroxine and triiodothyronine


major metabolic hormone, controls rate glucose is converted, important in normal growth and development, targets every cell



thyroid hormone in children

necessary for physical and mental development

thyroid hormone in adults

increases metabolic rate and temperature

goiter

thyroid hormone requires iodine from diet, if not enough iodine goiter forms

hypo secretion of thyroid hormone in kids

cretinism = dwarfism and metnal retardation

hypo secretion of thyroid hormone in adults

myxedema = sluggishness, fatigue, obesity, low temperature

hyper secretion of thyroid hormone

high metabolic rate, rapid heartbeat, heat intolerance, weight loss, agitation, bulging eyes

calcitonin

THYROID, THYROID C CELLS


peptide


targets bone, kidney


decreases calcium


causes a decrease in blood calcium by causing calcium to be deposited into bones; released directly into blood in response to increasing levels of blood calcium


production decreases w/ increasing age


antagonist of parathyroid hormone

parathyroid hormone (PTH, parathormone)

PARATHYROIDS


peptide


targets bone, kidney, small intestine


increases calcium


when calcium levels low, stimulates bone destruction to breakdown bone matrix and release calcium into blood; stimulates kidneys and intestines to absorb more calcium





hyper secretion of parathyroid hormone

massive bone destruction, fragile bones, spontaneous fractures

thymosin

THYMUS


peptide


*in children only*


causes development of normal immune system and T cell development during childhood

epinephrine (adrenaline) and norepinephrine (noradrenaline)

ADRENAL MEDULLA


modified amino acid; catecholamine


sympathetic stress response, rapid


very similar in effects, only different in target receptors



cortisone and cortisol (glucocorticoids)

ADRENAL CORTEX


steroids


promotes cellular metabolism and resists long term stressors and reduces inflammation and edema


longer term stress response; increases blood glucose concentration; increases protein catabolism; decreases inflammation and immunity







aldosterone (mineralocorticoid)

ADRENAL CORTEX


targets kidneys


increases sodium reabsorption to increase blood pressure


regulates mineral and salt content of blood and water and electrolyte balance

sex steroids

ADRENAL CORTEX


androgen - male sex steroid


estrogen - female sex steroid

adrenal tumor

sex steroids can be overproduced and cause masculinization or feminization

hypo secretion of aldosterone

addison's disease = bronze skin, H2O and sodium loss, weak muscles, shock

hyper secretion of aldosterone

hyperaldosteronism = excessive water and sodium retention; elevated blood pressure and edema; loss of potassium that affects muscle and heart function

insulin

PANCREAS (islets of Langerhans); B CELLS SECRETE


peptide


decreases blood glucose concentration; increases glycogen and fat storage


released by pancreas when glucose high; when blood sugar levels drop, insulin release stops

type I diabetes

body does not produce insulin, fixed with injections and pump

type 2 diabetes

insulin receptors unable to respond, fixed with special diet and exercise and injections if needed

glucagon

ENDOCRINE PANCREAS (Islets of Langerhans) ALPHA CELLS SECRETE


peptide


increases blood glucose concentration; decreases glycogen and fat storage


antagonist of insulin


targets liver to break down stored glycogen into glucose and release it into the blood

somatostatin (SS)

PANCREAS (islets of Langerhans) D CELLS SECRETE


peptide


secreted by D-cells in the pyloric antrum and the duodenum


inhibits many digestive processes

testosterone

TESTES


steroid


promotes male sex characteristics; necessary for sperm production

hypo secretion of testosterone

sterility

estrogen

OVARIES / PLACENTA


steroid


promotes female sex characteristics; promotes menstrual cycle (endometrial growth) and development of breasts

progesterone

OVARIES / PLACENTA


steroid


acts w/ estrogen to bring about menstrual cycle (endometrial secretion); keeps muscles of uterus quiet during pregnancy

atrial natriuretic factor (ANF)

HEART


peptide


targets the kidneys


increases urination to decrease blood pressure

erythropoietin

KIDNEYS


peptide


targets bone marrow


increases red blood cell production

melatonin

PINEAL GLAND


regulates sleep / wake and day / night cycles; coordinates fertility hormones; inhibits reproductive system development and sexual maturation before adult body size reached

relaxin*

PLACENTA


hormone that relaxes pelvic ligaments and pubic symphysis to widen the pelvis during delivery


*not on mcat list

human placental lactogen (hPL)*

PLACENTA


works with estrogen and progesterone to prepare breasts for lactation


*not on mcat list

human chorionic gonadotropin (hCG)*

PLACENTA


produced by developing embryo and fetal portion of placenta to continue estrogen and progesterone production


keeps the uterine lining intact


*not on mcat list