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8 Cards in this Set
- Front
- Back
Magnesium Sulfate Classification
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-Antiaarrhythmic
-Electrolyte |
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Magnesium Sulfate Mecahanism of Action
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-Second most plentiful intracellular cation. Essential for the activity of many enzyme systems and plays an important role with regard to neurochemical transmission and muscular excitability
-some effects on nervous system similar to those of calcium -Increased conc in extracellular fluid causes depression of CNS, has direct depressant effect on skeletal muscle -Low conc in extracellular fluid results in increased acetylcholine release and increased muscle excitability that can produce tetany |
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Magnesium Sulfate Mecahanism of Action--SA Node and effects on blood vessels
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-slows rate of SA Nodal impulse formation. Higher conc produce cardiac arrest in diastole
-causes vasodilation by direct action on blood vessels |
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Magnesium Sulfate Indications
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-Polymorphic VT with prolonged QT interval
-Rhythm control of AFib < 48 hours duration |
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Magnesium Sulfate Dosing
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-Torsades (pulseless): 1 to 2 g
-Torasdes (pulse)or Afib with rapid ventricular response: 1 to 2 g |
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Magnesium Sulfate Precautions
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-caution in patients recieving digitalis
-Caution in impaired renal function -caution with preexisting heart blocks |
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Magnesium Sulfate Contraindications
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-Respiratory depression
-Hypocalcemia -Hypermagnesemia |
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Magnesium Sulfate Special Considerations
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-S/S-Hypotension
-Flushing, sweating -bradycardia, AV block -Respiratory depression -Drowsiness, decreasing LOC -diminished reflexes or muscle weakness, flaccid paralysis -Antidote = Calcium |