Lymphatic System

Front 1

whats does the lymphatic system do

Back 1

defends the body

Front 2

what does the lymphatic system contain

Back 2

cells, tissues, and organs

Front 3

what does lymphocytes do

Back 3

resist infection and disease

Front 4

primary function of the lymphatic system

Back 4

production, maintenance, and distribution of lymphocytes

Front 5

color of lymph and compare to what

Back 5

clear, colorless, like plasma with less proteins

Front 6

lymphatic vessels are closed in

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one end

Front 7

what is tethered to surrounding tissue

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protein filaments

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ENDOTHELIAL CELLS LOOSELY

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OVERLAPPED

Front 9

how many classes of lymphocytes

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Three, T, B, NK

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T

Back 10

thymus dependent
80%

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B

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(bone marrow-derived) cells ( 15% )

Front 12

NK

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(natural killer) cells ( 5% )

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Lymphocyte production
Involves

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bone marrow, thymus, and peripheral lymphoid tissue

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B cells and NK cells mature in

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bone marrow

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T cells mature in the

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thymus

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Connective tissue dominated by lymphocytes

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LYMPHOID TISSUE

Front 17

Lymphocytes densely packed in areolar tissue

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Lymphoid nodules

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Lymphoid nodules
Found in the

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respiratory, digestive, and urinary tracts

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MALT

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(mucosa-associated lymphoid tissue)

Front 20

Collection of lymphoid tissues linked with the digestive system

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MALT

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function in the purification of lymph ( Filter the lymph )

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LYMPH NODES

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carry lymph to nodes

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Afferent lymphatics

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carry lymph from nodes

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Efferent lymphatics

Front 24

Deep cortex dominated by

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T cells

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Outer cortex and medulla contains

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B cells

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THE THYMUS
Located

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behind sternum in anterior mediastinum

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Capsule

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THE THYMUS

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Two lobes

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THE THYMUS

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Divided into lobules, each with a cortex and medulla

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THYMUS lobes

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Cortical lymphocytes surrounded by

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reticular endothelial cells

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thymus barrier

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Maintain blood

Front 32

Secretes thymic hormones

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THYMUS

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thymosins, thymopoietins, and thymulin

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thymic hormones

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Largest mass of lymphoid tissue

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THE SPLEEN

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Cellular components form

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pulp

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Red pulp contains

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RBC

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White pulp similar to

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lymphoid nodules

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Removal of abnormal blood cells and other blood components

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THE SPLEEN

Front 39

Storage of iron

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THE SPLEEN

Front 40

Initiation of the specific immune response (Filters the blood, Quick to detect antigens )

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THE SPLEEN

Front 41

broadly effective, no prior exposure.

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NONSPECIFIC DEFENSES

Front 42

protect against particular threats, depend upon the activation of lymphocytes

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SPECIFIC DEFENSES

Front 43

Keep hazardous organisms outside the body

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PHYSICAL BARRIERS

Front 44

Includes hair, epithelia, secretions of Integumentary and digestive systems

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PHYSICAL BARRIERS

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Remove cellular debris and respond to invasion by foreign pathogens

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PHAGOCYTES

Front 46

Fixed and free

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Monocyte-macrophage system

Front 47

Move by diapedesis

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PHAGOCYTES

Front 48

Exhibit chemotaxis

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PHAGOCYTES

Front 49

Constant monitoring of normal tissue by NK cells

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IMMUNOLOGICAL SURVEILLANCE

Front 50

Recognize cell surface markers on foreign cells

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NK cells

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Destroy cells with foreign antigens

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NK cells

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cytokines

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INTERFERON

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Small proteins released by virally infected cells

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INTERFERON ( cytokines )

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Trigger the production of antiviral proteins

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INTERFERON ( cytokines )

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Three major types of interferons are:

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Alpha
Beta
Gamma

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produced by leukocytes and attract/stimulate NK cells

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Alpha

Front 57

secreted by fibroblasts causing slow inflammation

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Beta

Front 58

secreted by T cells and NK cells stimulate macrophage activity

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Gamma

Front 59

Cascade of 11 plasma complement proteins (C)

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COMPLEMENT SYSTEM

Front 60

Destroy target cell membranes

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COMPLEMENT SYSTEM