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81 Cards in this Set

  • Front
  • Back

functions of the liver

metabolizes glucose


makes blood clotting factors


cleanses blood drugs chemicals and bacteria


synthesizes builliribin


synthesis and store bile

bile is a

digestive enzyme

jaundice/ lcterus

caused by abnormally high levels of bilirubin in the blood

elevated bilirubin levels

excessive destruction of RBC in the body



the liver is diseased and cannot excrete bilirubin normally

2 types of bilirubin measured in the blood

indirect and direct

indirect bilirubin

normally found circulating in the blood


when elevated the usual case is hemolysis


ex newborn infants

direct bilirubin

when this is elevated it's because of liver dysfunction or an obstruction somewhere btw the liver and small intestines



gallstones or cancerous tumor



ex cirrhosis or the liver

cirrhosis

degenerative lover disorder caused by damage to the liver cell



liver cells are irreversibly damaged and replaced by nonfunctional scar tissue which causes the liver to malfunction

3 types of cirrhosis

laennec


postnecrotic


billary

laennec

most common type


can be caused by chronic alcohol abuse, metal poisoning or acetaminophen overdose

postnecrotic

caused by infections such as hepatitis

biliary

obstruction or infection of Hillary tract

assessment for cirrhosis

symptoms worsen as disease progress


hepatomegaly


jaundiced skin,sclera and mucous membranes


ascites


chronic fatigue and anemia


clay colored stool


upset GI


tea colored urine


pruritis

diagnosis for cirrhosis

liver biopsy


blood clotting studies


lft


direct and indirect bilirubin levels


ammonia levels



ammonia is produced by protein

ammonia is converted to

urea

ammonia levels in the blood rise when?

the liver is not able to convert ammonia to urea

urea is eliminated In the

urine

ALT &AST

when damaged or destroyed they will leak into the blood where they can be measured by blood test

if AST&ALT are found together in the blood the what is suspected

liver damage

AST

is found in muscles and many other tissues beside the liver

ALT

is almost exclusively found in the liver

what does BUN stand for

Blood Urea Nitrogen

medical management for cirrhosis

vitamin K supplements (IV and IM)


lactulaose


laxative and ammonia detoxant


diuretics, fluid and sodium restrictions


blood transfusion to correct anemia


consider liver transplant

nursing management for cirrhosis

daily weight


measure abdominal girth (ascites)


good skin care

complications of cirrhosis

portal hypertension


esophageal varices


ascities


hepatic encephalopathy

portal hypertension is causes

esophageal varices


rectal hemmroids


caput medusal

portal hypertension

increased congestion and fluid pressure in the portal circulation this causes ascites



affects esophagus rectum and abdomen

what needs treated that are caused by portal hypertension

esophageal varices


ascites


hepatic encephalopathy


esophageal varices

dilated bulging esophageal veins


occurs as a result of portal hyper tension


esophageal varices may bleed from

alcohol use,rough food, insertion of NG tube is contraindicated

diagnosis for esophageal varices

barium swallow, esophagoscopy

treatment for esophageal varices

injection sclerotherapy , variceal banding



insertion of a sengesteken blakemore tube

sengstaken blakemore tube

needs to be inflated and deflated at diffrent intervals



KEEP scissors at bed side to cut the esophageal balloon and remove immediately

treatment for ascites

sodium restrictions


albumin replacement


paracentesis


spironolactone -diuretic


potassium sparing diuretic


denver shut


paracentesis

have the pt sitting upright so they dont have there intestines punctured

denver shunt

last resort high failure rate


pt must lay flat for several hours


when finished sit in semi fowler's to stop pump


distributes fluid into cardiovascular circulation

hepatic encephalopathy

neurological complications that often lead to coma and death



caused by high ammonia levels


can cause alteration and permanent damage to the CNS

assessment for hepatic encephalopathy

disorientation, mental confusion, personality changes, memory loss, asterisxis- tremor of the hands



percent neurological damage- kernicterus

treatment for hepatic encephalopathy

low protein diet


antibiotics to destroy bacteria that produce ammonia


neomycin kantrex


use of lactulose

hepatitis

Inflammation of the liver



most common is a viral infection



viral or due to chronic alcohol abuse

hepatitis B

infected by blood and sexual contact



symptoms rash may be asymptomatic


often fatal


high risk of liver cancer, cirrhosis

assessment for hepatitis

preicteric


icteric


posticteric

preicteric

N,V anorexia, weight loss,RUQ pain, hepatomegaly, spleenomegaly, rash pruritus

Icteric

symptoms as above + onset of jaundice, clay colored or whitish stools dark urine

posticteric

liver enlargement, fatigue, malaise persist, all other symptoms start to subside

diagnosis for hepatitis

serum testing for antibodies made against the hep virus



elevated liver enzymes


elevated bilirubin level


liver biopsy

medical management for hepatitis

bed rest, balanced diet


liver transplant


medications

hepatitis a

fecal to oral


raw sewage, sushi, sharing utensils, cigarettes



flu like symptoms, malaise, anorexia



full recovery

hepatitis c

infected blood, sexual contact


similar to hep b symptoms


often chronic


lead to liver cancer

meds for hepatitis

Ribavarin, Introl A, Roferon


Sofosbuvir- hep c 89% cure rate



hep c comb drug


lediposavir/sofobovir


SE: weakness, HA, fatigue check LFT

tumors of the liver

abnormal mass of cells in the liver may be malignant or benign



metastalises from somewhere else



tumor cells rapidly multiply causing


jaundice liver failure


portal hypertension


ascites

assessment for tumors

anorexia and weight loss


abnormal bleeding

if the tumor is refined to only one lobe you can have a

hepatic lobectomy

medical management of tumor

may be considered for a liver transplant


aggressive chemotherapy

gallbladder disorders

billary system


cholelithiasis


choledoxhilithiasis


cholecysitis

billary system

gallbladder and bile ducts which carry common bile into duodenum

cholelithiasis

formation of stones in the gallbladder

choledocholithiasis

stones present in gallbladder and common bile duct

choleytitis

inflammation or infection of the gallbladder

pathophysiology of gallbladder disorders

linked to high fat, high cholesterol diet



multiple pregnancies, diabetes, and obesity



most often happens in middle age women

when do symptoms develop with gallstones

when they partial or totally impair passage of bile from the gallbladder to the duodenum

a patient is eating fatty foods what hormone stimulates the gabaldder to contract and secrete bile into the duodenum

CCK

this aides in digestion of fats

bile

biliary colic

pain that accompany with contraction

early gallbladder symptoms

excessive belching


RUQ pain may radiate to back and shoulder


abd cramp after eating fatty foods

acute cholecystitis symptoms

fever, nausea vomiting


RUQ abd pain and back pain

diagnosis for gallbladder

ultrasound


ERCP


elevated bilirubin levels


leukocytosis


elevated liver enzymes


CCK

CCK

most often ordered for gallbladder

CCK

most often ordered for gallbladder

cholecystectomy

removal of gallbladder

a pt just had there gallbladder removed and is still complaining of back, shoulder and abdominal pain. what might be a way to help relieve there pain.

have the patient ambulate

chronic management for gallbladder

low fat diet

acute cholecystitis

NPO,IV fluids, angesics

3 digestive enzymes

amylase,lipase,tripsin

if the digestive enzymes are trapped in the pancreas what begins to happen

they begin to auto digest the pancreas

pancreatitis

inflammation of the pancreas needs to be treated ASAP

causes of pancreatitis

chronic alcohol use


tumors


unknown develops spontaneously

complication of pancreatitis

hyperglycemia


pain



infection,necrosis and hemmorage of the gland

assessment of pancreatitis

mild abdominal pain


N,V flatulance


steatorrhea


jaundice


absent or decreased bowel sounds


ascites

diagnosis of pancreatitis

election amylase


elevated serum bilirubin levels


CT MRI


hyperglycemia

management of pancreatitis

bed rest


encourage pt to sit up or lean forward


IV


IV ATB



analgesics


DON NOT GIVE MORPHINE


accuchecks