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13 Cards in this Set

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Which enzyme is activated by PKA that releases free fatty acids in adipocytes?

Hormone-sensitive lipase.

What is the substrate of hormone-sensitive lipase?

Diacylglycerols.

What is the function of perilipin and how is it regulated?

Perilipin covers the lipid droplets in adipose tissue to prevent enzymes from breaking down the lipids.


When perilipin is phosphorylated by PKA it floats away and no longer protects the lipid droplets, so lipolysis can occur.

Which enzyme is activated after perilipin is phosphorylated?

Adipose triglyceride lipase

Which molecule is essential for transport of free fatty acids in blood?

Albumin

Which molecule is essential for transport of free fatty acids into mitochondria?

Carnitine

Which lipoprotein is the largest?

Chylomicron

Which lipoprotein is the smallest?

HDL

Which lipoprotein contains the most triglycerides?

Chylomicrons

Which lipoprotein contains the most cholesterol?

LDL

Which lipoprotein contains the most protein?

HDL

Which enzyme is inhibited by steroids regarding pain killers?

Steroids inhibit phospholipase A2.

Which enzyme is inhibited by non-steroidal anti-inflammatory drugs (NSAIDs) regarding pain killers?

NSAIDs inhibit cyclooxygenase.