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26 Cards in this Set
- Front
- Back
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What are triglycerides?
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They make up most of the fats that humans digets. They are a single molecule of glyerol combined with three fatty acids.
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What are phospholipids used for in the body?
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They are used for building plasma membranes.
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How much cholesterol is required for daily intake?
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<300mg.
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What tranports lipids throughout the body?
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Lipoproteins.
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What is a bad lipoprotein?
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Low-density lipoprotein (LDL).
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What is the function of LDL?
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Transport cholesterol from liver to the tissues. They also store cholesterol in the lining of our blood vessels.
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What is the good lipoprotein?
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High-density lipoprotein (HDL).
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What is the function of HDL?
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They transport cholesterol away from tissues and to the liver and small intestine.
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What is hyperlipidemia?
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High levels of lipids in the blood.
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What should the total cholesterol level be?
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<200.
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What is the mechanism of action for a statin?
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Inhibits an enzyme that resultsin less cholesterol. The live then makes more LDL receptors, thus removing more LDL from the body.
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What are considered the drugs of first choice to reduce blood lipid levels?
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Statins.
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What is the common generic ending for statins?
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-statin.
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What is the common trade ending for statins?
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-or or -cor.
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Why should liver function be monitored when taking statins?
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Liver dysfunction may occur.
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What drug has the rare side effect of myopathy or rhabdomyolysis?
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Statins have this rare side effect.
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How do statins effect HDL levels?
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They raise them.
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Why are most statins administered in the evening?
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Cholesterol biosynthesis in the body is higher at night.
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Why is it best to take a statin at an evening meal?
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To avoid GI upset.
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How long does it take for a statin to yield positive results?
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About 2 weeks.
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Name a bile acid resin.
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Questran (cholestyramine).
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What is the mechanism of action of the bile acid resins?
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The resins bind with bile acids which are passed through the small intestine with feces.
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How do bile acid resins effect cholesterol?
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They accelerate cholesterol excretion via the GI track.
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Why should you avoid taking other meds with bile acid resins?
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These drugs tend to reduce the absorption of other drugs.
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Name a fibric acid agent.
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Lopid (gemfibrozil).
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What patients are best to receive fibric acid agents?
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Patients with excessive triglyceride and VLDL levels.
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