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32 Cards in this Set

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What are the characteristics of lipids?

-Contain hydrogen, carbon and oxygen


-Proportion of oxygen to carbon and hydrogen is smaller than in carbohydrates


-Insoluble in water


-Soluble in organic solvents e,g alcohols and acetone

What is the main groups of lipids?

Triglycerides


Phospholipids


Waxes

What are triglycerides?

Fats and oils

Where is the main function of lipids located?

In the plasma membrane

How do phospholipids contribute to the plasma membrane?

Helps flexibility


Transfer of lipid-soluble substances across membrane



What are the roles of lipids?

-Energy source- When oxidised, lipids provide more than twice the energy as the same mass of carbohydrate


-Waterproofing-Lipids are insoluble in water so therefore used as a waterproof


-Insulation- Fats are slow conductors of heat, when stored beneath the body surface they help to retain body heat


-Protection- Fat is often stored around organs

What is the difference between fats and oils?

Fats are solid at room temperature whereas oils are liquids

Why are triglycerides called triglycerides?

They have three fatty acids combined with glycerol

What reaction bonds the fatty acids to glycerol?

Condensation

What is produces when a triglyceride is hydrolysed?

Glycerol and three fatty acids

What is the structure of a triglyceride?

Why is there variation in triglycerides?

- Due to the fatty acids- Over 70 fatty acids


- All have a carboxylic group (-COOH) and hydrocarbon chain attached.


- If chain has no carbon-carbon double bond, fatty acid is saturated (all carbons linked to maximum number of hydrogens)


- If there is a single double bond it's mono-unsaturated


- If more than one double bond is present it's polyunsaturated


What is the difference between lipids and phospholipids?

In a phospholipid one of the fatty acid molecules is replaced by a phosphate molecule

Are fatty acid molecules hydrophobic or hydrophilic?

Hydrophobic- Repel water

Are phosphate molecules hydrophobic or hydrophilic?

Hydrophilic

What is a phospholipid made of?

Hydrophilic head- Attracted to water but not with fat


Hydrophobic tail- Orients itself away from water but mixes with fat

What is the test of lipids known as?

The emulsion test

How is the emulsion test carried out?

1. Take completely dry and grease-free test tube


2. Add 5cm of ethanol to 2cm of sample


3. Shake tube to dissolve and lipid in sample


4. Add 5cm of water and shake


5. Cloudy-white colour indicates presence of lipid


6. As a control, repeat procedure using water, final solution should remain clear

Why does the solution turn cloudy during the emulsion test if a lipid is present?

Lipid is finely dispersed in water to form emulsion


Light passing through this emulsion is refracted as it passes from oil droplets to water droplets

What is the cell-surface membrane?

The plasma membrane that surrounds cells and forms the boundary between cytoplasm and environment

What does the cell-surface membrane allow?

Allows different conditions to be established inside and outside of cell

What does the cell-surface membrane control?

Movement of substances

What do phospholipids form to create the cell-surface membrane?

Bilayer sheet

Why does one layer of phospholipids face inwards in a cell-surface membrane?

They have hydrophilic heads so they are attracted by the water in the cytoplasm

Why does one layer of phospholipids face outwards in the cell-surface membrane?

Hydrophilic heads are attracted to the water which surrounds all cells

Why do the hydrophobic tails point to the centre of the membrane?

So they are protected from the water

What are the functions of phospholipids?

Allow lipid-soluble substances to enter and leave the cell


Prevent water-soluble substances entering and leaving the cell


Make membrane flexible

How are protein molecules arranged in the cell-surface membrane?

Randomly


Embedded in the phospholipid bilayer in 2 ways


-Extrinsic protein (Partly embedded)


-Intrinsic protein (Go from one side to the other of bilayer)

What are the functions of extrinsic proteins?

Give mechanical support to the membrane


Work with glycolipids as cell receptors for molecules such as hormones

What are the functions of intrinsic proteins?

Act as carriers to transport water-soluble material across the membrane


Some are enzymes

What are the functions of the proteins in the membrane?

Provide structural support


Act as carriers transporting water-soluble substances across the membrane


Allow active transport across membrane by forming ion channels


Form recognition sites by identifying cells


Help cells adhere together


Act as receptors e.g for hormones

Why is the plasma membrane described as being a fluid-mosaic model?

Fluid- Individual phospholipid molecules can move relative to one another, membrane can constantly change shape



Mosaic- Proteins embedded in phospholipid bilayer vary in shape, size and pattern so it looks like a mosaic