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18 Cards in this Set
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What is the definition of prognosis?

Prediction of the expected outcome of a disease with or without treatment


The greek definition of prognosis in greek is to come to know beforehand, how is this possible?

Use population data to make a prognosis


What are the 5 things that a prognosis should include (ideally)?

1) The variability in course relative to treatment options
2) A time reference 3) Risk of treatmentrelated death (or other untoward reaction) 4) Cost 5) Nature of benefit attainable 

What is the definition of case fatality rate?

% of patients w/ a disease who die of it


What is the definition of survival rate?

% of patients surviving a defined period of time from some point in the course of their disease


What is the definition of response rate?

% of patients showing some evidence of improvement after an intervention


What is the definition of remission rate?

% of patients entering a phase in which disease is no longer detectable


What is the definition of recurrence rate?

% of patients who experience a return of disease after a diseasefree interval


What are the 2 questions that are the rationale for the life table?

1) What is the likelihood of surviving for x years after diagnosis
2) What is the likelihood of surviving another year, given that the patient has already survived for y years since diagnosis 

How do you calculte the cumulative probability of surviving different lengths of time?

It's a mutliplicative property so just multiple the probability of survival for each individual year
e.g. Probability of surviving 3 years= P1 x P2 x P3 

What does a survival curve show

Cumulative survival over time


How do you compare multiple survival curves?

Steeper slope= worse survival


Why can the tail towards the right side of a survival curve be deceiving?

Beause as the population decreases even with the same survival rate it will look like a not very steep slope


What is the yvalue of a survival curve?

Cumulative survival up to that time point


What does a survival curve show

Cumulative survival over time


How do you compare multiple survival curves?

Steeper slope= worse survival


Why can the tail towards the right side of a survival curve be deceiving?

Beause as the population decreases even with the same survival rate it will look like a not very steep slope


What is the yvalue of a survival curve?

Cumulative survival up to that time point
