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5 Cards in this Set
- Front
- Back
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Internalisation of L. monocytogenes |
Interaction with host cell receptors
Single protein adhesin -Protein adhesin: InIA -Host cell receptor: E-cadherin -Internalisation driven by changes in host cell's F-actin cytoskeleton |
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Internalisation of Salmonella enterica |
Injection of bacterial effectors
Type III system -Will inject equivalent of GAP and GEF proteins into the cell to exploit and control the cytoskeleton to allow for internalisation of the bacteria |
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Salmonella GAP equivalent |
SopE/E2 -It will cause the addition of GTP onto human G-protein and stimulate it |
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Salmonella GEF equivalent |
StpP -It will cause addition of GDP onto human G-protein and turn it off |
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Toxoplasma gondii |
-causes encephalitis in immunocompromised -causes abortions in pregnant women -first site of infection - epithelial cells lining intestine -internalisation is caused by gliding motility |
