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22 Cards in this Set
- Front
- Back
Friedrich Miescher |
characterized proteins from pus cells |
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Friedrich Miescher |
isolated a molecule from the nucleus and called it nuclein |
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Ernst Haeckel |
who said : “the obvious cellular component of the cell is the nucleus” ? |
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Edmund Wilson |
used staining technique to study karyokinesis of ovum
important nuclear element from cell to cell : DNA |
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Edmund Wilson |
used staining technique to study karyokinesis of ovum
important nuclear element from cell to cell : DNA |
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Rosalind Franklin, Gosling & Maurice Wilkins |
Found out that helical DNA structure, sugar, and phosphate background outside, while nucleotides are tucked inside |
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James Watson and Francis Crick |
Found out about triple helix, and that phosphate is in the center (pero lol mali naman haha nice try gg) |
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Linus Pauling |
proposed triple helix (epal) |
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John Griffith |
Proposed that nucleotides are flat, stack up on top of another, and the possibility of A=T, C=G pairing.
Crick saw the importance of specific pairing in replication process. |
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Erwin Chargaff |
proposed Chargaff’s rule
claims that purine-pyrimidine ratio is 1:1 |
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Jerry Donohue |
Claimed that hydrogen in the bases can change its position. (It may be responsible for the Hydrogen bonding) |
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Molecular Structure of Nucleic Acid
and
Genetic Implications of the Structure of Deoxyribuncleic Acid |
2 Publications of Watson and Crick |
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James Watson, Francis Crick, and Maurice Wilkins
(Rosalind Franklin was robbed frfr) |
Who were the ones who received a nobel prize? |
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Frederick Griffith |
transformation experiment using Streptococcus pneumoniae
transformed avirulent strain to virulent
declared the presence of transforming principle |
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Oswald Avery, Colin Macleod, Maclyn McCarty |
Physician-Scientists
identified the transforming principle (TP) as DNA |
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Alfred Hershey and Martha Chase |
used the blender experiment
proved that the DNA is the genetic material of bacterial viruses which is injected into the cell during infection |
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Norton Zinder and Joshua and Esther Ledenberg |
used transduction experiment in Salmonella typhimurium to further prove that DNA is the genetic material |
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Rosalind Franklin, Maurice Wilkins, James Wateson, and Francis Crick |
Discovered the structure of the DNA
(elucidated the DNA structure) |
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Francis Crick |
had PhD in Biophysics and worked on xray studies of proteins at Cambridge University |
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James Watson |
PhD in Microbiology from Univ of Indiana then moved to Cambridge Univ. then shared office with Crick |
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Maurice Wilkins |
PhD in Physics worked on radar and Manhattan Project and asst. Director of Med Research at Kings College, London
He worked on x-ray diffraction of DNA. |
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Rosalind Franklin |
Expert on x-ray diffraction techniques and joined Kings College in 1951 to work on x-ray diffraction of DNA |