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11 Cards in this Set

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Low potency ,short duration

Procaine


Chlorprocaine

Intermediate potency and duration

Lidocaine


Prilocaine

High potency, long duration

Tetracaine


Bupivacaine


Ropivacaine


Dibucaine

Surface anesthetics

Soluble: cocaine,lidocaine,tetracaine,proparacaine



Insoluble:


Benzocaine,butylaminobenzoate,ozethazaine

Lidocaine

Onset 3 mins..


Intense and longer


CNS effect: drowsiness mental clouding,dysphoria,altered taste and tinnitus.



Overdose:muscle twitching, convulsions, cardiac arrhythmia, fall in bp, coma , respiratory arrest

Prilocaine

Like lidocaine


Onset 15 mins...


Does not cause vasodialation.


Lower CNS toxicity( high Vd and fast clearance)



May cause Methaemoglobinemia..

Bupivacaine

More lipophilic.


Slow onset..


Epidural - painless delivery (also not affect fetus. Y?)



Prolong QT, induce ventricular tachycardia..


Highly cardiotoxic( trt: lipid emulsion infusion)

Levobupivacaine : s enantiomer..less cardiotoxic

Ropivacaine

Long acting congener of bupi.


Less cardiotoxic and CNS toxic


Lower lipid soluble


Differential block... sensory first

Tetracaine (amethocaine)

Highly lipid soluble PABA ester.


More potent and MORE TOXIC( slow hydrolysis by plasma pseudocholinestrase...



Contraindicated in Bronchoscopy

Proparacaine(proxymetacaine)

Opthlamic anasthetic

Uses and techniques

1.surface anesthesia


2.infiltration anesthesia


3.conduction


Field block


Nerve block


4.spinal anesthesia


5.epidural anesthesia


6.intravenous regional anesthesia