Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
bioavailability |
percentage of the drug dosage that is absorbed. |
|
drug absorption |
entrance of a drug into the bloodstream from its site of administration. |
|
drug addiction |
condition of drug abuse and drug dependence that is characterized by compulsive drug behavior. |
|
drug dependence |
condition of reliance on the use of a particular drug, characterized as physical and / psychological dependence. |
|
drug distribution |
passage of a drug from the blood to the tissues and organs of the body. |
|
drug excretion |
elimination of the drug from the body |
|
drug metabolism |
the enzymatic biotransformation of a drug into metabolites. |
|
drug microsomal metabolizing system (DMMS) |
group of enzymes located primarily in the liver that function to metabolize drugs. |
|
drug tolerance |
decrease drug affect occurring after repeated drug administration. |
|
enzyme induction |
increase in the amount drug metabolizing enzymes after repeated administration of certain drugs. |
|
enzyme inhibition |
inhibition of drug metabolizing enzymes by certain drugs. |
|
first-pass metabolism |
drug metabolism that occurs in the intestines and liver during oral absorption of drugs into the systemic circulation. |
|
half-life |
time required for the body to reduce the amount of drug in the plasma by one half. |
|
individual variation |
difference in the effect of drug and drug dosages from one person to another.
|
|
intramuscular (IM) injection |
route of drug administration; drug is injected into gluteal or deltoid muscles. |
|
intravenous (IV) injection |
route of drug administration; drug is injected directly into a vein. |
|
loading dose |
initial drug dose administered to rapidly achieve therapeutic drug concentrations. |
|
maintenance dose |
dose administered to maintain drug levels in blood in the therapeutic range. |
|
oral administration |
route of drug administration by way of the of the mouth through swallowing. |
|
parenteral administration |
route of drug administration that does not involve the gastrointestinal (GI) tract. |
|
pharmacokinetics |
describes the processes of drug absorption, drug distribution, drug metabolism, and drug excretion. |