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10 Cards in this Set

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--- Q1 – Human Implantation --- 8 15 23-30
A --- Describe formation of HUMAN placenta(drawings)?
1) How many pictures? 3
2) What times? #/#/# ***
3) Corresponding to? ***/***/*** ***
3a) last one.... c*** v*** c*** form

4) Name major components bottom to top?
------E***-*** ***
------C***
------S***
------E*** --- invades primary ***
------c*** v*** c***

5) Function of trophoblast?
----trephein: to *** --- blastos: ***
----i***
----Facilitates *** of n***, w**, g*** and !***!

6) Function of placenta?
!!!!!!!!!!!!!Endocrine Function
--------hormones produced by ***
------*** - keeps uterus *** and full of blood vessels
----c*** *** - placental lactogen
--***: P*** hormone causes p*** production

7)!!!!!!!!Protection From Maternal Immune System
---------*** inhibits Immune Response to *** type foreigner
-----Secretes *** blocking *** production
-Promotes I.R. suppressing ***(***)
-----*** Specific *** *** protects embryo from r***
1) 3
2) 1st/2nd/3rd week
3) primary/secondary/tertiary villus
3a) chorionic villi capillaries

4)------Extra-embryonic mesoderm
------Cyto trophoblast
------Syn cytio trophoblast
------Endometrium --- villus
------chorionic villi capillaries

5) Function of trophoblast?
----feed - germinator
----Implantation
----exchange ---nutrients --- wastes --- gases --- !IgG!

6) Function of placenta?
!!!!!!!!!!!!!Endocrine Function
--------Chorion
------Progesterone --- thick
----Chorionic somatomammotropin - placental lactogen
--Gonadotropin: Peptide --- progesterone


7)!!!!!!!!Protection From Maternal Immune System
---------Chorion --- allograft
----- proteins --- Ig
-lymphocytes(Treg)
----- Placental --- histocompatible Ig --- recognition
--- Q2 - Mammalian cleavage ---
--- Describe 5 Unique Properties? Most crucial? Why? ---

1) *** of cell ***
1a) One of *** in *** ***
1b) First *** takes # ***

2) *** c***
2a) Unique *** of ***
2b) 1st = *** ***
2c) 2nd = one *** / one ***

3) *** of *** cell division
3a) b*** don't *** @ s*** ti**.... therefore no *** g***

4) *** genome active early
4a) *** and g***(species) switch @ *** stage

5) *** at *** stage followed by *** and ***
5a) *** *** creates a tight compact ball... with *** ***
5b) Cells w/in ball form *** *** allowing transfer of s***l *** and ***
1) Slowness --- division
1a) slowest -- animal kingdom
1b) cleavage --- one day.

2) Rotational Cleavage
2a) orientation --- blastomeres
2b) 1st = meridional division
2c) 2nd = meridional --- equitorial

3) Asynchrony --- early
3a) blastomeres --- divide @ same time --- exponential growth

4) zygote genome active early
4a) Mouse --- Goat --- 2-cell stage

5) Compaction --- 8-cell --- morula --- blastula
5a) Tight Junction --- maximum contact
5b) gap junctions --- small molecules --- ions
--- Q3 - AA ---
--- AA ---

1)
1)
--- Q4 - Twins --- 8 – 25
--- 2Chorion:2Amnion --- 1Chorion:2Amnion --- 1Chorion:1Amnion ---

MAJOR COMPONENTS?
1) Step 1 - ***

2) Step 2 - *** *** ***

3) Step 3 - *** *** *** ***

4) Step 4 - *** *** ***
--- Q4 - Twins --- 8 – 25
--- 2Chorion:2Amnion --- 1Chorion:2Amnion --- 1Chorion:1Amnion ---

MAJOR COMPONENTS?
1) 2-cell embryo

2) Blastocoel, Inner cell mass, Trophoblast

3) Embryo, Yolk sac, Amnion, Chorion

4) Fetus, Amnion, Chorion
--- Q5 - Eye --- 9 - 35
--- Draw pigmented retina, neural retina, lens, and cornea ---

1) How many pictures?
2) Optic vesicle becomes a.........................
3) In the process the *** *** is induced.

Picture 1
1) *** of ***

Picture 2
1) *** of *** w/*** *** on far right/left
2) and *** *** on inside of open space

Picture 3
1) *** *** is not hollow
2) and the *** *** is spooning it

Picture 4
1) Everything is ***.
1) 4
2) two-walled optic cup
3) lens vesicle

Picture 1
1) Ace of Clubs

Picture 2
1) Ace of clubs --- lens placode
2) Optic Vesicle

Picture 3
1) Lens vesicle
2) Optic cup

Picture 4
1) normal
--- Q6 – SSH in eye --- 9-37

1) TF SHH influences *** development in *** *** through its ***.
2) If gene is mutated causing.... expression to be...
3) None = *** eye called *** .
4) Too much = *** too much area causing *** eye

4) *** *** Fish
5) Cavefish have large *** and little ***.
6) Normal fish have large *** and little *** .

8) It is believed SHH from *** *** suppresses *** in *** of field causing it to ***
--- Q6 – SSH in eye --- 9-37

1) field --- eye placode --- suppression
2)
3) One --- cyclopia
4) suppresses --- no

5) Mexican Tetra Fish
6) large Pax2 --- little Pax6.
7) large Pax6 --- little Pax2

8) prechordal plate --- Pax6 --- center --- divide
--- Q7 – Brain Development --- 9-16

1) Forebrain - *** encephalon
1a) ***encephalon – *** - Memory
1b) ***encephalon – *** - Vision

2) Midbrain - ***encephalon
2a) ***encephalon – *** - Habituation

3) Hindbrain - ***encephalon
3a) ***encephalon – *** - Muscle movement
3b) ***encephalon – *** -Respiration
--- Q7 – Brain Development --- 9-16

1) Pros
1a) Tel – Hippocampus
1b) Di – Retina

2) Mes
2a) Mes – Midbrain

3) Rhomb
3a) Met – Cerebellum
3b) Myel – Medulla Oblongata
--- Q8 - Hair ---
1) Formed from *** and ***?
2) Creating *** and ***?
3) ---- Stage 1 - !*** ***! is induced to become *** by !*** ***!. Tissue surrounding everything is !*** ***!
4) --- Stage 2 --- !*** *** ***! formed
5) --- Stage 3 --- D*** induces !*** ***! to divide rapidly. Soon !*** of ***! is surrounded by !*** hair ***!
6) --- Stage 4 --- !*** *** is formed lubing the !*** w/*** hair *** *** cells!. *** transfer pigment to the !***! *** cells
7) --- Types of Hair ---
8) *** – ***/*** spaced, *** before birth
9) *** – Remains on body and is ***
10) *** reverts back into ***
1) Epidermis and dermis
2) sweat glands and hair/scales/feathers
3)--- Stage 1 --- !Epidermal ectoderm! --- columnar --- !Condensed mesoderm! --- !Dermal mesoderm!
4) --- Stage 2 --- !Primary hair germ!
5) --- Stage 3 --- Differentiation --- !Dermal Papilla! --- !tip of hair! --- !Developing hair canal!
6) --- Stage 4 --- !Sebaceous Gland! --- !bulb w/pluripotent hair follicle stem cells! --- Melanocyte --- !hair! shaft cells
7)
8) Lanugo – Thin/closely --- shed
9) Vellus – hairless
10) Terminal – baldness
--- Q9 – Mice Primary and Secondary Neurulation --- 9 – 3-15

1) Primary neurulation – *** directs the *** above it to p***, i***, and p*** off from surface.
2) Secondary Neurulation - derived from *** *** of cells that *** and subsequently *** to form n*** t***

3) Illustrate Secondary Neurulation
a) *** of *** ***
b) *** w/*** anchored to ***
c) *** of *** ***
d) *** w/***
e) *** between *** and *** *** through *** *** cells
f) *** *** cells disperse

4) Illustrate Secondary Neurulation
a) !*** ***!
b) ***
c) *** ***
1) chordamesoderm --- ectoderm --- proliferate, invaginate, and pinch
2) solid cord --- sink --- hollows --- neural tube.

3) Illustrate Secondary Neurulation
a) Shaping of Neural Plate
b) Folding --- MedianHP --- notochord
c) Elevation of Neural Groove
d) Convergence w/Dorsal-LateralHP
e) Closure --- epidermis --- neural tube --- Neural Crest
f) Neural Crest

4) Illustrate Secondary Neurulation
a) !Medullary Cord!
b) Notocord
c) Neural Tube
--- Q10 – Neural Tube Dorsal-Ventral Specification ---
--- Describe Mechanism ---

1) SHH is a protein produced in *** for *** specification.
2) *** patterning *** SHH to *** region.
3) *** is produced in *** *** causing TGF-β ***.
4) Different *** of SHH:TGF-β causes *** of different *** *** giving cells their *** .
5) SHH *** expression of genes encoding *** ne*** *** specificity...

--- TGF-β --- located ***
*** ***(structure)
*** ***
*** ***
*** ***
*** ***
*** ***
*** neurons – TFs *** and ***
*** neurons – TFs *** and ***
--- SHH --- located ***
1) notochord --- ventral
2) Dorsal --- confines --- ventral
3) BMP4 --- roof plate --- cascade
4) levels --- expression --- transcription factors --- identity
5) represses --- dorsal neural tube

--- TGF-β --- dorsally in *** ***
D1 interneurons
D2 interneurons
D3 interneurons
V1 interneurons
V2 interneurons
Motor Neurons – TFs NKx6.1 and Pax6
V3 neurons – TFs NKx6.1 and NKx2.2
--- SHH --- ventrally in ***