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48 Cards in this Set
- Front
- Back
Cardiac myocytes deprived of blood supply start dying after how many minutes?
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20
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Death of the myocytes in a ____________________
myocardial infarction starts in the __________ zone, spreads in a wavefront to the ____________ zone and is usually complete after about _____________. |
Transmural (full thickness)
Subendocardial--> subpericaridal zone 3 hours |
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What is the ECG evidence of ischemia?
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ST-segment depression
T wave inversion |
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How long does it take for dead myocytes to show microscopic manifestations of their death?
What is the one exception? |
4 hours
Dead thin wavy myocytes my be visible as early as a half hour after infarction. |
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What are the three components of coagulative necrosis of dead myocytes in classic (UNREPERFUSED) myocardial infarction?
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1. Loss of normal cytoplasmic striations
2. Cytoplasmic hypereosinophilia 3. Nuclear changes (pyknosis, karyorrhexis, karyolysis, loss) |
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What is shown here?
What is this the earliest evidence of? How early can you see it? |
Thin wavy myocytes: sometimes present,
sometimes the earliest microscopic evidence of myocardial infarction, as early as 30 minutes after it has occurred |
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What is shown here?
What has not occurred yet? |
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