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11 Cards in this Set
- Front
- Back
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Angina symptoms |
Tightening of chest radiating to arms and neck Dizziness Nausea |
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What determines cardiac demand? |
Preload, afterload, myocardial workload |
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Stable angina caused by? |
An obstruction preventing blood flow usually caused by a stress and so is predictable |
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Unstable angina caused by? |
Happens at rest. Reduction of blood by clot formation as a result of plaque rupture. May be temporary blockage or may completely occlude intima |
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Adrenergic transmission in CVS |
Increased HR and force of contraction Increased preload by venous constriction Increased afterload by arterial constriction |
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What to do if you suspect MI? |
If symptoms last more than 20 mins do an ECG. ST elevation > assume MI and begin reperfusion Check for cardiac troponin in levels |
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What triggers thrombus formation? |
Plaque rupture releasing phosphatidyl serine triggering coagulation |
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How does NO work? |
Activates guanylate Cyclase, converting GTP to cGMP, blocking rise in calcium levels. |
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NO and MLCPhosphatase |
Triggers MLCPhosphatase to dephosphorylate mysosin head > relaxation |
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Low dose side effects |
Tachycardia |
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High dose side effects |
Flushing, headache |
