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11 Cards in this Set

  • Front
  • Back

Angina symptoms

Tightening of chest radiating to arms and neck



What determines cardiac demand?

Preload, afterload, myocardial workload

Stable angina caused by?

An obstruction preventing blood flow usually caused by a stress and so is predictable

Unstable angina caused by?

Happens at rest. Reduction of blood by clot formation as a result of plaque rupture.

May be temporary blockage or may completely occlude intima

Adrenergic transmission in CVS

Increased HR and force of contraction

Increased preload by venous constriction

Increased afterload by arterial constriction

What to do if you suspect MI?

If symptoms last more than 20 mins do an ECG.

ST elevation > assume MI and begin reperfusion

Check for cardiac troponin in levels

What triggers thrombus formation?

Plaque rupture releasing phosphatidyl serine triggering coagulation

How does NO work?

Activates guanylate Cyclase, converting GTP to cGMP, blocking rise in calcium levels.

NO and MLCPhosphatase

Triggers MLCPhosphatase to dephosphorylate mysosin head > relaxation

Low dose side effects


High dose side effects

Flushing, headache