Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
39 Cards in this Set
- Front
- Back
Two types of host defense systems
|
Innate & Adaptive immunity
|
|
First line of defense; nonspecific; always present
|
Innate immunity
|
|
Specific or acquired defense
|
Adaptive immunity
|
|
Two major classes of lymphocytes in adaptive immunity
|
B and T cells
|
|
Lymphocyte most responsible for the clearance of extracellular microbes.
|
B cells
|
|
Lymphocyte population most responsible for the clearance of intracellular microbes.
|
T cells
|
|
Classes of T cells
. |
Helper, Cytolytic, Regulatory
|
|
Substance, usually foreign, that reacts with an antibody
|
Antigen
|
|
Substance, usually foreign, that elicits an immune response.
|
Immunogen
|
|
Lymphocyte population that secretes antibodies
|
B cells (plasma cells)
|
|
Lymphocyte population that directly kills infected cells
|
Cytotoxic T cells
|
|
Lymphocyte population that helps B cells make antibodies
|
T helper cells
|
|
Lymphocyte population that helps activate macrophages
|
T helper cells
|
|
Active immunity that is naturally acquired.
|
Recovery from infection
|
|
Active immunity that is artificially acquired.
|
Vaccination
|
|
Passive immunity that is naturally acquired.
|
Placental transfer of IgG
|
|
Passive immunity that is naturally acquired.
|
Breast feeding of IgA
|
|
Passive immunity that is artificially acquired.
|
Injection of immune globulin
|
|
Maturation stage of a mature lymphocyte that has not yet engaged antigen.
|
Naive lymphocyte
|
|
Maturation stage of a mature lymphocyte that has been activated by antigen
|
Effector lymphocyte
|
|
Maturation stage of a mature lymphocyte that is long-lived and ready to rapidly respond to antigen on the second/subsequent exposures.
|
Memory lymphocyte
|
|
Secondary lymphoid tissue where the response occurs to blood-borne antigens.
|
Spleen
|
|
Secondary lymphoid tissue where the response occurs to tissue-borne antigens.
|
Lymph nodes, MALT, GALT, BALT
|
|
Major cell types involved in innate immunity
|
Granulocytes, macrophages, dendritic cells, NK cells
|
|
Neutrophils, eosinophils, basophils
|
Granulocytes
|
|
Primary lymphoid tissue
|
Bone marrow, thymus
|
|
Anatomic location where stem cells reside
|
Bone marrow
|
|
Anatomic site of B cell maturation
|
Bone marrow
|
|
Anatomic site of T cell maturation
|
Thymus
|
|
Cells that capture and present peptides to T cells
|
Antigen-presenting cells (APC)
|
|
Professional antigen presenting cells
|
Dendritic cells, macrophages, B cells, FDC
|
|
Response to first exposure to an antigen
|
Primary immune response
|
|
Response to repeat encounters with the same antigen
|
Secondary immune response
|
|
Major antibody produced in serum during primary immune response
|
IgM
|
|
Major antibody produced in serum during secondary immune response
|
IgG
|
|
Anatomic location of T cells in lymph nodes
|
Paracortex
|
|
Anatomic location of B cells in lymph nodes
|
Follicle (cortex)
|
|
Anatomic location of T cells in spleen
|
Periarteriolar sheath
|
|
Specialized venules in lymph nodes where T cells enter
|
High endothelial venules
|