Intro To Pharmacology (Test 1) Intro To Pharm

Front 1

What is pharmacodynamics (PD)?

Back 1

-The action of drugs on the body
-Involves: receptor binding, post-receptor effect, and chemical interaction

Front 2

What is Pharmacokinetics (PK)?

Back 2

-Actions of the body on a drug

Front 3

For PK, what does ADME stand for?

Back 3

-A: Absorption
-D: Distribution
-M: Metabolism
-E: Excretion

Front 4

What are excipients?

Back 4

Inactive substances used as a carrier for the active ingredient (drug substance)

Front 5

What is an orphan drug?

Back 5

A drug that targets a rare disease affecting fewer than 200,000 people.
-Rarely made due to cost/benefits

Front 6

How does the DEA organize controlled substances?

Back 6

-5 Schedules, 1 is most addictive with the highest dependence potential (ex. 1 = Heroine, Pot) (5 = Codine, cough preps)

Front 7

Which schedule has no medical uses?

Back 7

Schedule 1 (LSD, Heroine)

Front 8

Example of a Schedule 2?

Back 8

Morphine, Amphetamine

Front 9

Example of a Schedule 3?

Back 9

Ketamine, thiopental, anabolic steroids

Front 10

Example of a Schedule 4?

Back 10

Ambien

Front 11

Example of a schedule 5?

Back 11

Codine, cough preps

Front 12

What words can drugs use but supplements cant?

Back 12

-Protects
-Lowers
-Reduces
-Prevents

Front 13

What is
phase 1 of a clinical trial?

Back 13

-Safety (among small group of HEALTHY individuals)
-Pharmokinetics (dose range) (single/multiple/food effect)

Front 14

What is phase 2 of a clinical trial?

Back 14

-Safety (among larger group of patients with DISEASE or condition)
-Efficacy (optimal dose/schedules)

Front 15

What is phase 3 of a clinical trial?

Back 15

-PROVE Safety (Long! 3 yrs, Thousands of patients)
-PROVE Efficacy

Front 16

What is phase 3 of a clinical trial?

Back 16

-Post-Marketing Studies