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17 Cards in this Set

  • Front
  • Back

pharmacology

the mechanism of action, uses and unwanted effects of drugs on living tissue

Drug

a substance that modifies the activity of living tissue

Physiology

science of how living tissue functions

Therapeutics

study of the uses of pharmacological agents in disease states

Pathology

study of how the body goes wrong in disease states

Agonist

drug or naturally occurring body substance that directly causes a measurable response (excitatory or inhibitory)

Affinity

binding of agonist/antagonist to its receptor

Efficacy

ability of agonist to activate the receptor

chemical antagonist

when 1 antagonises the action of another by chemical combing with it

pharmacological antagonist

when drugs counteract each other by acting on the same receptor

physiological antagonist

when 2 drugs counteract each other by producing opposing effects on different receptors

latrogenicity

the capacity to produce disease from the side effect or inappropriate prescribing of drugs

tetragenicity

the capacity to produce abnormalities of the unborn child

Drug targets

1. Ion channels


2. Enzymes


3. Transporters/carriers


4. Receptors

verapmil

cardiac Ca+ channel blocker

ibuprofen

cylo-oxygenase inhibitor

Prosac

5-HT uptake inhibitor