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23 Cards in this Set

  • Front
  • Back
If MRSA is present in a Health-Care Associated Intrabdominal infection then need to add
Vancomycin
If enterococcus is colonized in a Health-Care Associated Intrabdominal infection then need to add _____ and especially in _____ patients
Ampicillin
Piperacillin-Tazobactam (Zosyn)
Vancomycin

Especially in immunocompromised, post op patients, recent ceph use, prosthetic heart valve
If candida albicans is present in Health-Care associated intraabdominal infection then need to add
fluconazole
If non-candida albicans or fluconazole-resistant isolates are present in Health-Care associated intra-abdominal infection then need to add
caspofungin
micafungin
andulafungin

(CMA - candida minus albicans)
For Health-Care Associated IA infections need to cover ___ & ____ so treat with _____
Enteric G(-) rods (enterobacter) & anaerobes
imipenem-cilastatin, meropenem, or doripenem

Piperacillin/Tazobactam

Ceftazidime or Cefepime + metro

Aminoglycoside + metronidazole
Define Primary peritonitis and what is it also known as
Spontaneous Peritonitis - an infection w/o an evident source in the abdomen
Acoholic cirrhosis is most commonly associated with what type of peritonitis
Primary Peritonitis (usually enteric organisms)
E. Coli
Streptococcus spp.
Klebsiella
peritoneal dialysis (gram - bacilli)
Define Secondary Peritonitis and what 3 things may it involve?
A focal disease process is evident within the abdomen

Perforation of the GI tract
Postoperative Peritonitis
Post-Traumatic Peritonitis (blunt or penetrating trauma)
This is the most common cause of secondary peritonitis
Appendicitis
True or False: Abscess must present with bacteremia
False - abscess may not present with bacteremia
Most common organism in an intra-abdominal abscess
Bacteroides Spp (B frag)
What potential pathogens should be suspected with Primary peritonitis?
E. Coli
streptococcus spp
Klebsiella
What potential pathogens should be suspected with Secondary Peritionitis?
aerobes: KEEP
Klebsiella, E. Coli, Enterobacter, Proteus

Anaerobes:
Bacteriodes
Peptostreptococcus
Fusobacterium
Clostridium

Fungal: Candida Albican
What potential pathogens should be suspected with Abscess
Aerobes:
E. Coli
Proteus
Klebsiella

Anaerobes:
Bacteroides spp
What are the 3 drugs that B frag is resistant to?
Clindamycin
cefotetan
Aztreonam

B Frag is most common in all 3 types of infections!
What is early mortality from an intra-abdominal infection influenced by?
Aerobic Bacteria!
____ antibiotic therapy is administered if an infection is suspected
Presumptive (Empiric)
____ antibiotic therapy is administered as treatment of an infection
Therapeutic
What are the most common pathogens associated with Surgical Site Infection's
Staphylococcus aureus 20%
Coagulase-negative staphylococci
Enterococci
E. Coli
Pseudomonas
What is the most common cause of nosocomial acquired multiresistant organisms?
Hospital Personnel
May need to redose if surgery is ___ hours
greater than 3 hours
For vancomycin or fluoroquinolones start infusion ___ prior to incision
60 to 120 minutes
Prophylaxis agent should be administered ____ prior to incision
with anesthesia (usually 60 minutes prior to incision)

Agent should be delivered to surgical site prior to incision