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6 Cards in this Set

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Colecalciferol + digoxin

Increased risk of digoxin toxicity

Warfarin & St John's wort

SJW decreases anti acog effect of warfarin- less blood thinning, more chance of clots- LOW INR

LOW INR

Warfarin & Trimethoprim

Trimet increases anticoag effect of warfarin- more blood thinning- more bleed risk- HIGH INR

High INR

Warfarin & imidazole antifungals e.g. Ketoconaxole, Fluconazole,Miconazole

Imidazole increase anti coag effect of warfarin- More blood thinning- more bleed risk- HIGH INR



Community pharmacy- if pt asks for miconazole oral gel for mouth ulcers etc.- check for warfarin

High INR

Warfarin and which juice interact and how (inhibitor or inducer)

Cranberry juice - inhibitor - increases warfarin conc- increases anticoag effect

Sildenafil and enzyme....

Inhibtors (sickfaces.com


Sidenafil metabolised by CYP3A4- so cimetidine, riafmpicin, ketoconazole, itraconazole, erythromycin, diltiazem