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34 Cards in this Set

  • Front
  • Back
What kind of virus is a calicivirus

a. RNA virus with rapid mutations and minimal rates of repair so has increased amount of strains
308
Severity of disease depend on what three factors

a. Strain of FCV involved
b. Infecting dose
c. Host immunity
309
What benefit do the vaccines give

a. Reduce clinical signs
b. No effect on infection or shedding
310
What clinical sign are they commonly associated with

a. Stomatitis
b. Polyarthritis
c. Lameness
311
Secretions reach what radius when sneezed

a. 4 feet
b. Spread via fomites
312
What is unique about shedding and testing them

a. Shed for months
b. 50% of shedding occurs in 15 days
c. Need to wait 2.5mos between tests to determine if shedding has stopped
313
What are poor prognostic factors

a. Jaundiced
b. Dyspnea
c. 50% mortality
314
What are the clinical signs

a. Pyrexia
b. Edema
c. Crusting/ulceration on
i. nose
ii. Lips
iii. Periocular skin and distal limbs
d. Pleural effusion
e. Icterus
f. V/D
315
How is FCV diagnosed

a. Virus isolation-oropharyngeal swab
b. Culture
c. Serology (not recommended b/c of high exposure rate but can run convalescent titers)
316
How should one clear the environment

a. Bleach will inactivate the virus
317
Intranasal vaccine is available

a. Yes, killed antigen only
318
What is barrier nursing

a. Working from least to most infected area
b. Sneeze barriers
c. Quarantine area
319
What type of virus is herpes virus

a. DNA virus with 1 serotype (FHV-1)
320
Latent infections are kept wehre

a. Trigeminal ganglion
321
How long does a cat shed herpes virus after stress

a. 7-10 days occurs for 1-2 weeks
322
How does L-lysine work

a. Competes with Arginine in the formation of the herpes virus particle and decreases shedding
323
Pythiosis and lagenidiosis are classified as what type of fungi

a. Water molds: Oomycetes
324
How do they reproduce

a. Motile, flagellated zoospores
325
How are they different from other fungi

a. Lack chitin in cell wall
b. Lack ergosterol in cell membrane
326
What type of clinical syndromes do they cause

a. Eosinophilic pyogranulomatous inflammation
327
How do they appear in tissues

a. Irregularly, branching sparsely septate hyphae
328
Where is pythium found routinely

a. SE US
b. Often fatal
329
Which types of dogs are mostly affected

a. Large, young dogs
330
After encountering the mobile zoospore, how does the organism get into the dog

a. Encyst in damaged skin or GI mucosa
331
What are the two main forms of disease

a. GI
i. Segmented transmural thickening of the GIT
1. Pylorus
2. Proximal duodenum
3. Ileocecal junction
ii. Mesenteric lymphadenopathy
iii. Mass at root of mesentery
b. Cutaneous
i. Non healing wounds with draining tracts
ii. Regional lymphadenopathy
iii. Extension of post surgical recurrence
332
What layers of the GIT are mostly affected

a. Submucosa and muscularis layers -> may be missed on endoscopic biopsy
333
How is it diagnosed

a. Identification of hyphae in or near the mass
i. Readily seen with GMS stain
b. Culture- grown w/in 12-24 hours on right media
c. PCR-done on cultured organisms
d. ELSIA
i. Has high sensitivity and specificity-detects anti Pythiosis antibodies @ LSU and helpful for monitoring therapy too
1. Should drop by 50% in 2-3 months
334
What is the treatment

a. Aggressive surgery
335
What degree of margins are necessary

a. 3-4 cm
b. Biopsy or remove lymph nodes
336
How common is recurrence

a. Common so treat for 2-3 months
i. Itraconazole and terbinafine (have to use both)
337
Lagenidiosis has how many species

a. 2
i. Uniformly fatal dermatologic and disseminated dz
ii. Chronic ulcerative nodular dermatopathy (less common)
338
What types of lesions are found in the fatal form

a. Occult lesions in chest or thorax
b. Invasion of vessels leading to hemoabdomen and death
339
How is this diagnosed

a. Cytology or histopath-> hyphae seen on H&E stain, larger than pythiosis
b. Serology (cross reactivity w/ pythiosis and other fungal diseases so not recommended often)
c. Culture-Best way to diagnose-> differentiates between pythiosis and this
340
What is the treatment

a. Aggressive surgical resection with wide margins followed by itraconazole and terbinafine