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10 Cards in this Set
- Front
- Back
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What are some lab tests that may help dx osteo? |
elevated WC elevated sedimentation rate elevated C-reactive protein |
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What are some diagnositic tests that can help dx osteo? |
radiographic tests: positive results lag behind infectious process CT or MRI radionuclide imaging: positive as soon as 24-48 hrs after infections process begins |
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What should be used empirically for neonates? |
neonates < 1 mo i. nafcillin plus cefotaxime; or ii. nafcillin plus an aminoglycoside |
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empiric treatment for infants? |
infants 1-36 mos i. cefuroxime ii. ceftriaxone iii. nafcillin plus cefotaxime |
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empiric for peds? |
peds older than 3 i. nafcillin ii. cefazolin iii. clindamycin |
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empiric for adults? |
nafcillin cefazolin vanco |
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What abx are best for pts w/ sickle cell anemia? |
ceftriaxone/cefotaxime or cipro/levoflox **no studies assessing best empiric therapy |
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How should prosthetic joint infections be treated? Staphylococcal infxn? |
pathogen specific IV therapy plus rifampin 350-400 mg BID for 2-6 wks, followed by rifampin plus cipro/levoflox for 3 mos (hip, elbow, shoulder, ankle) or 6 mo (knee) |
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How should prosthetic joint infections be treated? Nonstaphylococcal infxn? |
pathogen specific IV or highly bioavailable oral therapy for 4-6 wks, followed by indefinite oral suppression therapy |
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What is the criteria for effective po therapy for osteo? |
1. adherence 2. identified organism that is highly susceptible to po abx 3. c-reactive protein < 2.0 mg/dL 4. adequate surgical debridement 5. resolving clinical course |
