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7 Cards in this Set

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  • Back
What would Vm look like for a local potential along an axon? Why does this happen?
Would fade out over time and distance (not enough to depolarize cell and open Na+ channels; leak out of ion channels along the way)
What motivation do ions have to move along an axon?
Ionic repulsion
Describe the path of ions when injected into an axon.
Propel along bc of ionic repulsion, collect at membrane bc membrane acts as capacitor.
Assume threshold is reached during depolarization of a neuron, describe the graph of an action potential using E values as reference points.
Starts at Vm, Na+ channels open, depolarize toward E of Na+, Na+ channels close, K+ channels open, approach E of K+ (beneath initial Vrest), K+ channels close, Na+/K+ pump works back up to Vrest
Why don't K+ channels open at same time as Na+ channels?
K+ channels are delayed rectifier channels; open more slowly in response to depolarization
What is the absolute refractory period? When does it occur?
Na+ channels are inactivated and cannot be re-opened no matter what the stimulus; occurs under spike in action potential graph
What is the relative refractory period? When does it occur?
Have to stimulate harder to get an AP; occurs during Na+/K+ pump part of graph to get back up from hyperpolarization