Immunology - Test Ii - Lymphocytes, Lymphoid Tissues, And Maturation (5)

Front 1

4 key features of lymphocytes

Back 1

Circulate
Individual AG receptors in plasma membrane
Clonal proliferation
Confers memory to adaptive immune system

Front 2

Two primary divisions of T-lymphocytes

Back 2

Tαβ
Tγδ

Front 3

Which class of T-lymphocytes is divided into CD4 and CD8?

Back 3

Tαβ

Front 4

Primary function of B lymphocytes

Back 4

Secrete ABs

Front 5

AG receptors for B lymphocytes

Back 5

Membrane bound immunoglobulin

Front 6

Identifying surface molecules for B lymphocytes

Back 6

IgA, IgB

(AKA CD79a and CD79b)

Front 7

Location of B lymphocytes in secondary lymphoid tissues

Back 7

Follicles/nodules

Front 8

Location of T lymphocytes in secondary lymphoid tissues

Back 8

Diffuse tissue

Front 9

AG receptors for T lymphocytes

Back 9

TCR

Front 10

What is the identifying surface molecule located on all T-lymphocytes?

Back 10

CD3

Front 11

What is the identifying surface molecule located on all helper T-lymphocytes?

Back 11

CD-4

Front 12

What is the identifying surface molecule located on all cytotoxic T-lymphocytes?

Back 12

CD-8

Front 13

Function of Th1 T-lymphocytes

Back 13

Activate macrophages

Front 14

Function of Th2 T-lymphocytes

Back 14

Activate eosinophils

Front 15

Function of Th17 T-lymphocytes

Back 15

Activate neutrophil

Front 16

Function of Tfh T-lymphocytes

Back 16

Activate B lymphocytes

Front 17

Which MHC class is associated with B lymphocytes?

Back 17

MHC Class II

Front 18

Which MHC class is associated with CD4?

Back 18

II

Front 19

Which MHC class is associated with CD8?

Back 19

I

Front 20

Primary Lymphoid Tissues (4)

Back 20

- Thymus
- Bone Marrow
- Ileal Peyer's patches
- Cloacal bursa

Front 21

Where do all lymphocytes originate from?

Back 21

Bone marrow

Front 22

Where do T lymphocytes mature?

Back 22

Thymus in all species

Front 23

Where do B lymphocytes mature in the bird?

Back 23

Cloacal bursa

Front 24

Where do B lymphocytes mature in primates and rodents?

Back 24

Bone marrow

Front 25

Where do B lymphocytes mature in ruminants, pigs, and dogs?

Back 25

Ileal Peyer's patches

Front 26

Secondary Lymphoid tissues (3)

Back 26

- Spleen
- MALT
- Lymph nodes

Front 27

Function of the spleen

Back 27

Filters blood-borne AGs

Front 28

Function of MALT

Back 28

Filters AGs entering at mucosal surfaces

Front 29

Function of lymph nodes

Back 29

Filters AGs in lymphatics

Front 30

Where are B lymphocytes generally found?

Back 30

Nodular/follicular structures

Front 31

Where are T lymphocytes generally found?

Back 31

Diffuse lymphatic tissue

Front 32

What type of lymphocytes circulate between blood and secondary lymphoid tissues?

Back 32

Naive

Front 33

Where do mature memory lymphocytes generally go?

Back 33

Back to the tissue they were activated in

Front 34

MALT stands for?

Back 34

Mucousal Activated Lymphatic Tissue

Front 35

Where does the problem with maturation of lymphocytes come from?

Back 35

Rearrangement of receptor genes is somewhat random, allowing for self recognition by accident

Front 36

Name for the process of selecting against self-recognition T-lymphs

Back 36

'Negative selection'

Anything that tests strongly against self dies.

Front 37

Three possibilities of positive selection in T lymphocytes

Back 37

CD 4
CD 8

Death

Front 38

Four possibilities of negative selection in T lymphocytes

Back 38

Th
Tc
Treg
Death