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30 Cards in this Set
- Front
- Back
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Primary lymphoid organs |
Cells develop bone marrow and thymus |
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Secondary lymphoid organs |
Cells activate spleen, lymph nodes, MALT, CALT |
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Bone marrow |
Lymphs produced from precursor stem cells B lymphs mature T cells migrate to thymus |
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Thymus |
T cells mature |
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Red pulp of spleen |
macrophages removes rbc |
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White pulp of spleen |
Site of antibody production and antigen specific T cells |
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Effector T cells |
Produce cytokines |
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Memory cells (activated T cell) |
Prepared to produce cytokines |
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Primary follicles |
Unstimulated B cells marginal zone of white pulp |
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Secondary follicles |
Stimulated B cells marginal zone of white pulp |
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Plasma cells |
Antibody producing activated B cells |
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Memory cells (activated B cells) |
Prepared to produce antibody |
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Lymph nodes |
Filters lymph fluid for antigens and site of antigen-lymph interaction |
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Cortex of lymph nodes |
Concentration of B cells |
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Paracortex of lymph nodes |
Site of T cells |
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Antigen stimulation |
Lymph comes in contact with specific antigen |
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Mucosa associated lymphoid tissue (MALT) |
GI, respiratory, urogenital tract |
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Cutaneous associated lymphoid tissue (CALT) |
Under skin epithelia |
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MALT and CALT |
Intercepts invaders that enter body by different routes |
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Antigen independent lymphopoiesis |
Bone marrow - primary lymphoid organ |
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Antigen dependent lymphopoiesis |
secondary lymphoid organs |
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periarteriolar lymphoid sheath (PALS) |
contains most of white pulp in spleen |
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central zone of white pulp |
T cells |
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marginal zone of white pulp |
B cells |
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lymphadenopathy |
lymph node enlarges due to antigen stimulation |
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Antigen stimulation - 1st sequence |
specific lymphs retain in LN |
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antigen stimulation - 2nd sequence |
lymphs activated to proliferate/differentiate |
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antigen stimulation - 3rd sequence |
lymphadenopathy |
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antigen stimulation - 4th sequence |
Tc cells migrate to battle site |
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antigen stimulation - 5th sequence |
plasma cells remain to secrete antibodies to enter circulation |
