Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
|
*What causes peripheral lymphoid tissues to become populated with B & T cells
|
Chemokines
|
|
|
Describe spacial and temporal regulation of B cell activation
|
a
|
|
|
What is the role of the medullary area?
|
a
|
|
|
What is the role of the B cell area?
|
a
|
|
|
What is the role of the T cell area?
|
a
|
|
|
What is the role of the primary focus?
|
a
|
|
|
What is the role of the germinal center?
|
a
|
|
|
What role do follicular dendritic cells play in humoral immunity?
|
a
|
|
|
What are some characteristics of follicular dendritic cells?
|
a
|
|
|
In regards to BCR antigens - what are the three different classes?
|
Thymus dependent
TI-1 TI-2 |
|
|
What is the outcome of stimulation by a thymus dependent antigen?
|
a
|
|
|
What is the outcome of stimulation by a TH-1 antigen?
|
a
|
|
|
What is the outcome of stimulation by a TH-2 antigen?
|
a
|
|
|
What are some important molecules involved in thymus dependent B cell activation?
|
Signal 1
Signal 2 CD40:CD40L |
|
|
A _________ B cell differentiates into a ___________ which differentiates into a ____________
In the event an antigen reoccurs _________ B cells can be activated |
Resting, Plasma blast, Plasma Cell
Memory |
|
|
Describe linked recognition
|
a
|
|
|
Describe passive immunity
|
a
|
|
|
Describe somatic hypermutation
|
a
|
|
|
Describe class switching
|
a
|
|
|
What are some key characteristics of IgM?
|
aa
|
|
|
What is the first immunoglobulin produced?
|
IgM
|
|
|
What are some key characteristics of IgG?
|
a
|
|
|
What are some key characteristics of IgD?
|
a
|
|
|
What are some key characteristics of IgA?
|
a
|
|
|
What are some key characteristics of IgE?
|
a
|
|
|
Name three effector functions of antibodies
|
Neutralization, opsonization, complement activation, ADCC, mast cell activation
|
|
|
What is ADCC
|
Antibody-dependent Cell cytotoxicity
|
