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4 Cards in this Set

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  • Back

4 Types of Cytokines

1. TNF


2. Chemokines


3. IFN


4. Hematopoietin

5 Families of Cytokine Receptors

1. Immunoglobulin Superfamily - disulfide bonds


2. Class I Chematopoietin - conserved cysteines and WSXWS


3. Class II (IFN) - 4 repeating Cys


4. TNF Receptor - Many repeating Cys


5. Chemokines - G protein + transmembrane domain

Pleiotropy

When 1 cytokine has multiple targets

Redundancy

A cytokine has redundancy when many cytokines have the same effect