Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
NMB Reversal Drugs
|
The Wake Up; Induction drugs long gone, turned gas off so that is gone too, need to get rid of NMBs; Anticholinesterase Drugs prevent the hydrolysis of Ach, and an increase [Ach] @ NMJ competes with ND NMBDs; clinical uses--reversal of Non-depol NMBDs; Mech.
of action--enzyme inhibition, pre-synaptic effects, NMJ effects; get this increase [Ach] everywhere though, so get the BLUDS effect--attenuate by using in combination w / Anticholinergic drugs; BLUDS= bradycardia / bronchospasm, lacrimation, urination, defication, salivation; Anticholinergic Drugs used clinically most often as pre-op med, for treatment of bradycardia, for NDNMB reversal and less frequently for bronchodialation, smooth muscle relaxant, antagonist of gastric acid secretion, & to prevent N / V; work by blocking muscarinic Ach receptors activated by parasymp. NS, careful though....will cause dialation of pupils (worsens Glaucoma) and will cross placenta in pregnant woman (Cautions=Glaucoma / Parturients). (Parturient=pregnant woman) NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Drug (trade name) |
Neostigmine
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Class |
Anticholinesterase
NMB Reversal Drugs Group 9 |
|
|
Anticholinesterase
|
A substance that blocks the activity of the enzyme cholinesterase, increasing the concentration of acetylcholine in the body.
An _____ inhibitor or _____ is a chemical that inhibits the cholinesterase enzyme from breaking down ACh, increasing both the level and duration of action of the neurotransmitter acetylcholine. |
|
|
Neostigmine
Uses |
NMB REVERSAL
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
[ Supplied ] |
1mg / ml or 0.5 mg / ml
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Dosing--card |
0.04mg / kg
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Dosing--Stever |
0.04-0.07mg / kg
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Caution |
BLUDS , Hypotension
NMB Reversal Drugs Group 9 |
|
|
Neostigmine
Notes |
NMB Reversal Drugs
Group 9 |
