Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/10

Click to flip

10 Cards in this Set

  • Front
  • Back
NMB Reversal Drugs
The Wake Up; Induction drugs long gone, turned gas off so that is gone too, need to get rid of NMBs; Anticholinesterase Drugs prevent the hydrolysis of Ach, and an increase [Ach] @ NMJ competes with ND NMBDs; clinical uses--reversal of Non-depol NMBDs; Mech.
of action--enzyme inhibition, pre-synaptic effects, NMJ effects; get this increase [Ach] everywhere though, so get the BLUDS effect--attenuate by using in combination w / Anticholinergic drugs; BLUDS= bradycardia / bronchospasm, lacrimation, urination, defication, salivation; Anticholinergic Drugs used clinically most often as pre-op med, for treatment of bradycardia, for NDNMB reversal and less frequently for bronchodialation, smooth muscle relaxant, antagonist of gastric acid secretion, & to prevent N / V; work by blocking muscarinic Ach receptors activated by parasymp.
NS, careful though....will cause dialation of pupils (worsens Glaucoma) and will cross placenta in pregnant woman (Cautions=Glaucoma / Parturients).
(Parturient=pregnant woman)

NMB Reversal Drugs
Group 9
Neostigmine
Drug
(trade name)
Neostigmine

NMB Reversal Drugs
Group 9
Neostigmine
Class
Anticholinesterase

NMB Reversal Drugs
Group 9
Anticholinesterase
A substance that blocks the activity of the enzyme cholinesterase, increasing the concentration of acetylcholine in the body.
An _____ inhibitor or _____ is a chemical that inhibits the cholinesterase enzyme from breaking down ACh, increasing both the level and duration of action of the neurotransmitter acetylcholine.
Neostigmine
Uses
NMB REVERSAL

NMB Reversal Drugs
Group 9
Neostigmine
[ Supplied ]
1mg / ml or 0.5 mg / ml

NMB Reversal Drugs
Group 9
Neostigmine
Dosing--card
0.04mg / kg

NMB Reversal Drugs
Group 9
Neostigmine
Dosing--Stever
0.04-0.07mg / kg

NMB Reversal Drugs
Group 9
Neostigmine
Caution
BLUDS , Hypotension

NMB Reversal Drugs
Group 9
Neostigmine
Notes
NMB Reversal Drugs
Group 9