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10 Cards in this Set
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- Back
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NMB Reversal Drugs
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The Wake Up; Induction drugs long gone, turned gas off so that is gone too, need to get rid of NMBs; Anticholinesterase Drugs prevent the hydrolysis of Ach, and an increase [Ach] @ NMJ competes with ND NMBDs; clinical uses--reversal of Non-depol NMBDs; Mech.
of action--enzyme inhibition, pre-synaptic effects, NMJ effects; get this increase [Ach] everywhere though, so get the BLUDS effect--attenuate by using in combination w / Anticholinergic drugs; BLUDS= bradycardia / bronchospasm, lacrimation, urination, defication, salivation; Anticholinergic Drugs used clinically most often as pre-op med, for treatment of bradycardia, for NDNMB reversal and less frequently for bronchodialation, smooth muscle relaxant, antagonist of gastric acid secretion, & to prevent N / V; work by blocking muscarinic Ach receptors activated by parasymp. NS, careful though....will cause dialation of pupils (worsens Glaucoma) and will cross placenta in pregnant woman (Cautions=Glaucoma / Parturients). (Parturient=pregnant woman) NMB Reversal Drugs Group 9 |
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Atropine
Drug (trade name) |
Atropine
NMB Reversal Drugs Group 9 |
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Atropine
Class |
Anticholinergic
NMB Reversal Drugs Group 9 |
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Anticholinergic
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An _____ agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. An example of an .
is dicyclomine. . s are administered to reduce the effects mediated by acetylcholine on acetylcholine receptors in neurons through competitive inhibition. Therefore, their effects are reversible. |
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Atropine
Uses |
Bradycardia, accompany NMB Reversal to fight BLUDS
NMB Reversal Drugs Group 9 |
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Atropine
[ Supplied ] |
0.4, 0.5, 1mg / ml
NMB Reversal Drugs Group 9 |
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Atropine
Dosing--card |
1.0mg vagolytic dose; 0.01mg / kg NMB reversal
NMB Reversal Drugs Group 9 |
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Atropine
Dosing--Stever |
IM 0.01-0.02 mg / kg (up to 0.4-0.6 mg); Bradycardia 0.4-0.6mg (up to 3mg)
NMB Reversal Drugs Group 9 |
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Atropine
Caution |
Glaucoma, Parturients
NMB Reversal Drugs Group 9 |
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Atropine
Notes |
NMB Reversal Drugs
Group 9 |
