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158 Cards in this Set

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In what types of patients and in what areas of the body should you avoid using a local anesthetic with epinephrine?
Fingers, ears, nose, toes and hose (penis)

Not for periorbital block in people with closed angle glaucoma

Caution is people with: HTX, DM, PVD, thyrotoxicosis, or Cerebral vascular disease
In a patient who is allergic to Novocaine, can you use Xylocaine? Should you use the multidose vial or the single dose vial?
-Yes, because Novocaine is a Ester (more allergies) and Xylocaine is an Amide (less allergies) and the two groups do not cross-react

- Multidose vials of amides may have preservatives similar to esters. It is best to use a single dose
Does epinephrine extend or shorten the duration of a local anesthetic
Epinephrine will increase the duration of anesthetics because it constricts the vessels and keeps the drug from dissipating.
Which causes less pain: SubQ or intradermal injection?
Sub Q is less painful but takes longer to work.
What can you do to reduce the pain of an injection?
- Distract patient
- Use small needle
- Inject slowly
- Inject SubQ
- Add sodium bicarbonate to buffer anesthetic
- Warm solution
Pinch and shake skin during injection
- Us topical anesthetic prior to injection
How long does it take EMLA to work and can you use it on broken & unbroken skin
EMLA is a mixture of prilocaine and lidocaine
Onset is 1-2 hrs. and last for 1-2 hours
Used only for intact skin
May cause methamoglobinemia in G6PD and pts on sulfa drugs.
How long does it take for a digital nerve block to work?
5-10 minutes
Describe the direction of pressure used to loosen and lift an ingrown nail. Then describe the way that the nail is split and removed.
Upward
Roll it out of the nail bed then cut toward the cuticle
What is Phenol used for and what complication can occur with it?
- Chemical cauterization of the germinal tissues of the nail bed.
How do you differentiate a subungual hematoma from a subungual melanoma, splinter hemorrhages, and green nail syndrome?
Melanomas are linear (longitudinal) and pigment may extend to the soft tissue (hutchinson's sign)

Subungual hematomas are horizontal and never pigment the soft tissue of the cuticle
Describe the difference between the procedure for removing a 1-barb versus a 2-barb fish hook.
Single Barb: 1)Anesthesia over the tip of the hook 2) Advance it 3) Clip the tip off with wire clippers 4) then back the hook out.

Double Barb Hook: 1) Push point through the skins 2) Cut off the back part of the hook 3) advance the rest of hook all the way through the skin
How do you pull out a tick and what should you avoid doing?
1) paint around the area with betadine
2) Grasp the tick as close to the skin surface as possible and pull outward away from the skin

- Do NOT twist, jerk, squees or crush tick.
Know how to perform a punch biopsy and how you know if you are through to the subQ tissue
1) Clean area
2) Ring of anesthesia around lesion
3) Use punch that is 2 mm larger than lesion
4) Punch larger than 4mm usually requires a suture.
5) A decrease in resistance will indicate that you have passed through to the dermis. Plug should pop up above the skin surface.
How many mm beyond the margin of the lesion must you freeze for a benign lesion?
For small or flat lesions, start with a freeze for 5-10 secs, until a 1-3mm ice ring forms around the lesion.
What are the disadvantages and contraindications to cryotherapy?
Disadvantages:
- Destroys melanocytes
- Destroys hair follicles
- Area is more susceptible to sunburn
- Superficial nerve damage

Contraindications:
- Melanoma
- Recurrent basal or squamous cell cancers
- Patient requests
Relative Risks:
- Cold intolerance/ Raynaud's
- Cold uticaria
- Cryglobulinemia
- Heavily pigmented skin
- lesions in pretibial, eyelids, nasolabial folds, hair bearing areas
What type of suture is best for skin and what size is used on the body?
4-0 or 5-0 Nylon (Ethilon) that is monofilament and unbraided
What is the preferred technique for biopsy for pigmented lesions?
Excisional Biopsy
Why is a cervical polyp removed?
If they are large or symptomatic
When do you need to give tetanus immune globulin?
When patients have an unclear history of receiving the vaccine. Igs when there is less than 3 tetanus shots or an unclear history
What is Hutchinson’s sign?
- Streak of pigmentation under the nail that encompasses the cuticle which is a sign of melanoma.

- Shingles that encompasses the Tip of the nose.

- Notched teeth in a patient with congenital syphilis
Define diagnostic criteria for DMII
Must be confirmed on two occassions:
1) Fasting glucose >126
2) Abnormal OGTT > 200 at 2hrs
3) Random BG > 200
4) HgA1c > 6.5
How does HgA1c correlate to EAG (est. avg. glucose)
6 ~ 135 mg/dl
7 ~ 170
8 ~ 205
9 ~ 240
10 ~ 275
11 ~ 310
12 ~ 345
13 ~ 380
How effective are lifestyle changes in the management of DMII?
Best treatment
Define Macro and Microvascular diseases in DMII
Macro: due to hyperinsulinemia
- Cerebral Vascular accidents
- Heart disease
- Renal Artery stenosis

Micro: due to glucose levels
- Retinopathy
- Retinal Hemorrhages
- Cataracts
- Neuropathy
What is the initial treatment of DMII based on HgA1c > 7 vs. HgA1c > 9 with symptoms?
HgA1c > 7 use a dual therapy of medcations

HgA1c > 9 with symptoms: use triple therapy with insulin
What is the role of lipid lowering and blood pressure control in DMII, what medications are used?
Lipids: Reduces cardiovascular complications.

BP: reduces microvascular complications
Reduces heart disease and stroke
Reduces kidney problems
Define clinical findings of hyper and hypothyroidism.
Hyperthyroidism:Nervousness, irritability, tremors, heat intolerance, sweating, exophthalmos

Hypothyroidism: Fatigue, Cold intolerant, brittle hair, weight gain
What is the most common cause of hyper and hypothyroidism?
Hyperthyrodism: Graves disease

Hypothyrodism: Hashimoto's disease
What are the lab tests that correspond to hyper and hypothyroidism?
Hyper: Low TSH and high free T4 and T3

Hypo: High TSH and low T4 and T3 and Anti-TPO
What medications are used to treat hyper and hypothyroidism?
Hyper: Methimazole or Propylthiouracil for Pregnant pts

Hypo: Levothyroxine (T4)
What is the difference between Cushings Disease and Cushings Syndrome?
Syndrome: High levels of glucocorticoids and the effects

Disease: a specific cause for high corticoids which is Pituitary adenoma
What are the clinical findings in Cushings Syndrome, what are the lab tests used to diagnose?
ACTH is High with adenoma

ACTH is low with drug therapy or adrenal adenoma

Dx: 1) Demonstrate Elevated Cortisol
2) Identify cause (ACTH high or low)
I
What is the most common cause of Cushing’s Syndrome?
Exogenous glucocorticoid therapy
Compare and contrast Addison’s Disease with Hyperaldosteronism, what are some of the metabolic differences?
Addison's disease: Primary adrenal insufficiency, Pigmenation of skin
-Inadequate production of glucocorticoids, mineralcorticoids, and androgens. Autoimmune (most common)

Hyperaldosteronism: Idiopathic (most common cause) increased aldosterone and suppressed RAA system. Most common Secondary Hypertension
What is a pheochromocytoma, list common symptoms (5 P’s) and the labs associated with the diagnosis.
Palpitations
Perspiration
Pain - Headaches, tremors
Pallor
Pressure - Hypertension resistant to therapy
A defect in 21-hydroxylase enzyme will cause what substrate to increase?
17-hydroxyprogesterone which spills over to increase Androgens (virilization)
How is Pheochromocytoma diagnosed?
24 hour urine collection of Free Metanephrines and Catecholamines
When is hCG first detectable in a pregnant women?
8-10 days post fertilization
What is the fundal height for a 12wk and 20 wk pregnant lady?
12 = Barely above the pubic symphysis

20 = Umbilicus
What are the major drugs that should be discontinued during pregnancy?
Lithium - Malformed tricuspid, thyroid, neuromuscular system

Phenytoin - IUGR, cardiac defects, hypoplastic nails

ACEI - Renal tubular dysplasia, IUGR

Vitamin A - CNS defects, cleft lip, thymic agenesis
What are the cardinal signs of placenta abrupto?
Painful bleeding
Fetal distress
What are fetal reasons for induction of labor?
- IUGR
- Abnormal fetal testing
- Infection
- Rh incompatibility
- Oligohydramnios
What are the signs of separation of the uterus?
- Uterus becomes globular
- Gush of blood
- Uterus rises in abdomen
- Cord elongation
What are the methods of determining how strong the contractions are?
Palpation
External transducer
Internal Pressure Catheter
What are the four types of maternal pelvis?
1) Gynecoid - good
2) Anthropoid - good
3) Android - Poor
4) Platyepelloid - Poor
What are the cardinal movements of labor?
1) engagement
2) descent
3) Flexion
4) Internal Rotation
5) Extension
6) External Rotation
7) Restitution
What is Asynclitism?
Where the baby's head is tilted so that it is not in line with the birth canal.
What is the difference between a Frank Breech and a Complete Breech?
The Babies knees are flexed in complete and extended in Frank

Frank is more likely to deliver vaginally.
What are the major neonatal complications due to premature delivery?
Pulmonary hypoplasia
Respiratory Distress Syndrome
Intraventricular Hemorrhage
Necrotizing Enterocolitis
Systemic Infection/Sepsis
What are the 5 processes by which breast milk is carried out?
- Exocytosis
- Reverse Pinocytosis
- Transcytosis
- Apical Transport
- Paracellular movement
What is often the most common sign of Vulvar/vaginal hematoma?
Hemodynamic instability secondary to blood loss into the abdomen or pelvis
What are some causes of Postpartum fever?
Womb = endometritis
Water = pyelo, UTI
Walk = DVT, PE
Wind = atelectasis, pneumonia
Wound = infection from wound
Weaning = breast engorgement, mastitis, abscess
Wonder = Drug fever
What are the two most emergent conditions that must be considered in a woman of childbearing age who presents with abdominal / pelvic pain?
Hemorrhagic Shock (Ectopic preg)
Septic Shock (from PID)
What is the relationship of previous episodes of Pelvic Inflammatory Disease to future fertility?
The more episodes of PID the more infertile the patient becomes.
Complete this sentence: The diagnosis of ectopic pregnancy should be considered ....
In any women of childbearing age presenting with lower abdominal pain or pelvic pain.
What are the important areas of focus in the history of a woman of childbearing age presenting with abdominal / pelvic pain?
- Current Pregnancy status
- Menstration
- Prior pregnancies
- Dizziness and/or vomiting
- Fever
- Pain
What is the temporal relationship of nausea and vomiting in ectopic pregnancy as opposed to bowel obstruction and appendicitis?
Ectopic pregnancy: Occurs concurrently with pelvic pain

Obstruction/Append: Vomiting occurs before the onset of pain.
Discuss the history of radiation of pain in female with pelvic pain as it relates to several differential diagnoses.
Unilateral - Torsion, adnexal disease, cyst rupture, tubal inflammation

Radiation to back - retroperitoneal abscess, bladder infection, dysmenorrhea

Radiation to extremities - Fibroids, ectopic pregnancy, and dysmenorrhea
Discuss the timing and rate of onset of pain as it relates to several differential diagnoses for ectopic pregnancy.
Ectopic pain - Severe, continuous, unilateral pelvic pain that rapidl becomes diffuse.

PID - More insidious bilateral pain that progresses over days
What are the risk factors for ectopic pregnancy and for pelvic inflammatory disease?
Females between 20-30 y/o
Black enthicity
Previous PID secondary to GC
Current IUD use
Multiple sexual partners
Recurrent UTIs
Previous tubal pregnancy
Tubal surgery is associated with a 10 fold increase
Discuss the method of pregnancy testing used today that is most reliable and sensitive.
Quantitative hCG

- Sensitive to pregnancy detection after 7 days of conception. UAs are less reliable
Discuss the use of a complete blood count in the work-up of a female with abdominal / pelvic pain
The blood count may be normal even if the pt is bleeding since patients bleed whole blood.

A WBC shift may indicate infection or may be elevate from stress of the pain alone
Discuss the use of urinalysis in the work-up of the female with abdominal / pelvic pain.
Differentiate between UTI and Ureteral Cacluli from PID or ectpic pregnancy

Be aware that two diseases may co-exist (i.e. PID and Calculi)
What is the earliest that ectopic pregnancy be found on ultrasound?
- Transvaginal ultrasound is the most effective way for detecting an ectopic pregancy as early as 4-5 weeks.
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management of ectopic pregnancy
A) Severe, constant, unilateral pelvic pain, that rapidly becomes diffuse across entire lower abdomen and pelvis, Pain may radiate to shoulder

Occurs 5-8 weeks after LNMP
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management for pelvic inflammatory disease.
- Fever, Leukocytosis, purulent endocervical discharge. Associated with pelvic pain and tenderness
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management of endometriosis.
Constant pain beginning 2-7 days before menses which increases until menses flows. May radiate to back, thighs, rectum, bladder, vagina, oradnexa. Usually history of repeated attacks, associated with menses

Associated with infertility or sterility; painful defecations.
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management ruptured corpus luteum cyst / torsion of ovarian cyst
Sudden onset; initially severe, intermittent, and localized to one adenexa. becomes continuous with local pain then general peritonitis

No precipitating factors
Cyst rupture 6-8 wks from Last Normal Menstrual Period

Utlrasound may reveal pathology but laproscopy may be needed fro diagnosis

Cystic pain resolves after 2-4 hours
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management of degeneration of uterine fibroids / myomas
Sudden sever localized pain
Older females, especially blacks
Menorrhagia, intermenstrual bleeding, occasionaly dysmenorrhea or urinary frequency
Palpation of mobile non-tender, firm, smooth masses
Discuss pain history, precipitating events, associated symptoms, laboratory findings, and management of mittelschmerz
Sudden sharp, continous pain that is localized to one adnexa. May radiate to ipsilateral shoulder
The most common alternative to ectopic pregnancy with patient with positive hCG , abnormal pain and vaginal bleeding?
Threatened abortion
Make a diagnosis based on the results of the ELISA, Western Blot, HIV RNA or p24 antigen
ELISA - Not positive until 3-7 weeks

Western Blot - Confirmatory; may show none or one band during the acute phase

HIV p24 antigen - can detect before seroconversion

HIV viral load (PCR) - extremely high during acute HIV is positive 3-5 days earlier than p24 antigen.
When is a person usually symptomatic in acute HIV and how long does it last?
2-4 wks after infection and lasts 2-4 weeks
What does the rash of acute HIV usually look like and what is the distribution?
Maculopapular & symmetrical, primarily face and trunk. Usually does not itch
Is the risk of sexual transmission higher in acute or chronic HIV?
Acute - due to the high viral load
What causes a higher susceptibility to transmission?
Bacterial vaginosis
GC
Chlamydia
Candida
Trichomonas
Describe some of the most common signs and symptoms of a person presenting with acute HIV
Fever (most common)
General Malaise, fatigue, pharyngitis, weight loss, myalgias, headache, nausea, night sweats, diarrhea, vomiting, mucocutaneous ulcers and rash
When should a person be tested for HIV antibodies after a needle stick?
ASAP with ELISA to get a basline for a HIV negative serum

Follow-up with 6wks, 3 months and 6 months
In a high risk exposure setting(ie Needle stick), when should postexposure prophylaxis of HIV be initiated?
Within 36 hrs of exposure
Is it more common for a person with an acute HIV infection to be symptomatic or asymptomatic?
Symptomatic - 80-90% are symptomatic
What is the most common way to transmit HIV worldwide? in the US?
Worldwide - Heterosexual intercourse

US - Homosexual intercourse
How long after exposure is the HIV virus transported to the regional lymph nodes?
within 48-72 hours
What is it called when the HIV RNA levels and the immune system reach a steady state?
The viral set point

- occurs within 6 months of infection
What is the common clinical feature of a patient with Acute HIV?
Fever then fatigue
What is the definition of a:
Macule
Patch
Papule
Plaque
Nodule
Tumor
Vesicle
Pustule
Bullae
Pustule
Macule - <.5 cm change in skin color; not raised
Patch - > .5 cm change in skine color, not raised
Papule - raised but smaller than .5 cm
Plaque - Raised but larger than .5 cm
Nodule - firm lesion thicker and deeper than plaque or papule

Tumor - large nodule

Vesicle = Raise CLEAR fluid < .5 cm

Bullae - Raised CLEAR fludi > .5 cm

Pustules - Raised with pus
What is the difference between an erosion and an ulcers?
Erosion - burn, aphthous ulcer, herpes that only removes epidermis

Ulcers - Removes epidermis and dermis
Lichenification
Thickening of the skin
Desquamation
Peeling of the skin after acute injury - Steven-Jonhson's syndrome
What type of lesions would have a blanching color?
Uticaria and inflammatory lesions blanch

Hemorrhagic lesion (petichiae and purpure from vasculitis) do NOT blanch
What is the presentation, toxin and treatment that is involved with Loxosceles reclusa
Asymptomatic bite that becomes a large necrotic ulcer; summer

Toxin: Sphyngomyelinase D

Tx: Elevation and cold compress which slows down the toxin
What is the presentation, toxin and treatment for Latrodectus Mactans bite?
Sharp pinprick pain that becomes painless. CC: Muscle rigidity, abd cramps, pain and nausea. Anxiety

Toxin: a-Latrotoxin - neuotoxin which releases neurotransmitter

Tx: Cold compresses, Narcotics, possibly muscle relaxants
What is the presentation of a patient with fleas?
Lesions below the knees
Erythematous macules - pruritic
Lesions in groups of 3's
Fleas can lie dormant for a year

Tx: Steroidal creams and Antihistamines
What is the typical presentation of chiggers?
Stylostomes in the dermis where the larva attach
Intesnely red itchy papules develop after a delay of many hours

Usually a history of grass exposure
Tx: Vigorous cleansing to remove the larva, Topical steroids and antihistamines
What are the symptoms of Lyme disease?
Rash - erythema migrans (Targetoid)
Stage I - Influenza like symptoms (fatigue, myalgias, headache, fever

Stage II - Cardiac problems (arrhythmias and haert block, Bell's palsy)

Stage III - Arthritis and continued chronic neurological problems
What are the classic signs and symptoms and treatment of Scabies?
Debilitating itching that is worse at night
Excoriasion in the finger webs

Tx: Permethrin cream (Elimite) from neck down
What is the clinical presentation of Impetigo and the treatment?
Nonbullous or Bullous forms
Yellow crusts
Either by Staph or GABHS

Tx: Mupiroxcin TID for non-bullous or Dicloxacillin PO in bullous cases
What are the causes and treatment for Folliculitis?
Causes: Staph and Pseudomonas

Tx: Bactroban (mupirocin) or Dicloxacillin or cephalexin
What is the significance of the hutchinson's sign in Shingles?
Hutchinson's sign is the involvement of the tip of the nose and puts the patient at risk for serious ocular complications
What is the treatment for Shingles?
Acyclovir within 72 hours of onset of symptoms.
Zostavax vaccine for anyone 60 years and older
What complication occurs when a child < 5 years old gets HSV-1 around the oral area?
Gingivostomatitis
- fever, sorethroat, ulcerative lesions in and around the mouth and throat
What is Herpetic Whitlow?
Herpes infection of the distal fingers more frequently seen with health care workers
What is Herpes Gladiatorum?
Disseminated skin lesion often seen in wrestlers caused by HSV
What isoforms of Coxsackie cause Herpangina?
A2, A6-8, A10

A16 causes Hand-foot and mouth disease
What is Entropion? Ectropion?
Entropion - Inward turning of the eyelids (Chlamydia)

Ectropion - outward turning of the eyelids
What is the tx for Pinguecula and Pterygium?
Artificial tears

Topical vasoconstrictors

Surgery
What is the treatment for corneal abrasion due to Herpes Simplex?
Viroptic 5x daily
What are some common causes of bacterial Conjunctivitis?
Staphylococcus

Streptococcus

Haemophilus
What is the treatment for Bacterial Conjunctivitis?
Topical Antibiotics QID x 4 days

Warm Compresses
When should viral conjunctivitis be referred to a ophthalmologist?
If there's pain, photophobia or decreased vision
What are the different S/sx of someone with Pre-septal cellulitis vs. Orbital Cellulitis?
Pre-septal - vision, pupils and motility are normal

Orbital - Pain, fever, blurred vision, diplopia, limited motility, ABNORMAL pupil
What are the symptoms of tear deficiency?
Burining

Foreign-body sensation

Reflex tearing
What conditions are associated with Tear Deficiency?
Aging

Rheumatoid Arthritis

Steven-Johnson Syndrome

Systemic medications
Temporal Arteritis may cause what effects on the eye?
Ischemic Optic Neuropathy

Cranial Nerve Palsies

Retinal vascular occlusions
What symptoms indicate the need for an X-ray>
Gross deformity
Point tenderness
Swelling and ecchymosis
Decreased ROM of joint
Laceration or punture wound NEAR joint
At what age do the different parts of the elbow ossify?
Capitulum - 2 years
Radial Head - 4 years
Medial epicondyle - 6 years
Trochlea - 8 years
Olecranon - 10 years
Lateral epicondyle - 12 years
What are the complex bone fractures that are needed to refer to an orthopedist?
Spiral fx
Comminuted fx
Compression fx
Salter III/IV/V or displaced Salter I/II
Meralgia Paresthetica involves what nerve?
Lateral Femoral Cutaneous Nerve
What nerve is damaged in Tarsal tunnel syndrome?
Distal tibial nerve
What are some of the causes of Carpal tunnel syndrome?
Idiopathic - Most
RA
DM
Hypothyroidism
Repeated injury
Pregnancy
What are the medications used for Neuropathy?
Amitriptyline
Gabapenitin
Tylenol with codeine
Topical Capscasin
What is Mononeuritis multiplex?
Painful sensory and motor neuropathy involving at least 2 separate nerve areas

Associated with systemic diseases: DM, Vasculitis, amyloidosis
What is Diabetic Thoracic Radiculopathy?
Neuropathy that has a burning, stabbing, belt-like pain

Unilateral

May occur in 1 or more spinal roots
What are the cardinal signs of Parkinson's?
Resting tremor
Rigidity
Bradykinesia
Postural Instability
(asymmetric Onset)
What is the most common cause of a tremor?
Essential tremor
- unkown cause
- Symmetric and intentional (vs parkinson's) or isolated head tremor
- Family history is predictive
What are the non-motor symptoms of Parkinson's disease?
Psychosis or hallucinations (usually visual)
Mood disorders - depression
Sleep disturbances
Pain
Fatigue
Olfactory dysfunction
Dementia (20-40%)
What is the gene that is associated with MS?
HLA DRB1 - 1501

Allows lymphocytes into CNS

Adhesion moelcule is VLA4
What is the test done that can help dx MS?
Elevated IgG levels in CNS demonstrated by oligoclonal banding on electrophoresis
What are the common manifestations of MS?
Optic Neuritis - orbital pain and variable visual loss (may be exacerbated by heat)

Cerebellar Ataxia

Cortical hemiparesis

Facial nerve palsies inlcuding tic douloureux

Nystagmus and internuclear ophthalmoplegia
What other disease may mimic MS?
HIV
SLE
Vasculitis
Lyme disease
What is the treatment for MS?
Support - depression/suicide

Glucocorticoids for acute flares

Interferons - IFNB-1b, INFB-1a (inhibit INF-gamma activity)
What neurons are affects by ALS?
UMN - Precentral gyrus
- Spascticity, abnormal reflexes

LMNs - Anterior Horn of spinal cord
- muscle flaccidity, atrophy

Prefrontal neurons: cognition - loss of executive functions
What are the risk factors for ALS?
Smoking
Eating food products made from Cycad
What four regions of ALS?
Bulbar - Muscles of face, mouth and throat

Cervical - Muscle of neck, shoulders, upper extremities

Thoracic - Muscles of chest and abdomen

Lumbosacral - Lower back, groin, lower extremities
What are the clinical manifestations of ALS?
Progressive weakness to a certain region :
Bulbar - dysphagia, dysarthria, respiratory

Hyperreflexia: babinski, hoffman's sign

Fasciculations
What are 3 life-extending procedures done for someone with ALS?
Non-invasive ventilation

Percutaneous endoscopic gastrostomy - aspiration

Riluzole - Gluatmate pathway antagonis
Define diarrhea, inflammatory diarrhea, noninflammatory diarrhea, and acute and chronic diarrhea.
Diarrhea - Loose or watery stools >3/day or increased volume

Inflammatory diarrhea - Colic tissue damage

Noninflammatory - watery, nonbloody
Discuss the areas of focus in the history of a patient presenting with diarrhea.
Onset, duration
Stress related
Nocturnal diarrhea - Diabetic neuropathy
Frequency - fluid rehydration
Discuss the areas of focus in the physical of a patient presenting with diarrhea.
General Appearance - hydration, mental status

Vital signs

Abd exam - peritoneal pain?

Rectal - fistulas, fecal impaction
List the top 3 causes of inflammatory diarrhea due to bacterial tissue invasion.
1-3 days onset (similar to ETEC)

Salmonella - Food borne eggs, poultry, beef, veggies, fruit

Shigella - human to human

Campylobacter - Chicken (guillain barre syndrome)
List 2 causes of cytotoxin-induced inflammatory diarrhea.
EHEC - Shiga-like toxin attacks intestinal endothelial cells (beef, unpasteurized juice)

C diff - within 2 mos of Antibiotics

Vibrio Parahemolyticus - shell fish
List the causes of noninflammatory diarrhea due to food poisoning from a preformed enterotoxin.
S. Aureus - (1-6 hr incubation) prominent vomiting, lasts 24-48 hrs, Mayonnaise, creams/custards, meats

B Cereus - Emetic onset 1-6 hrs, Diarrhea onset 8-14, Last for 12-24 hrs. Rice and starches

C. perfringens - Diarrhea after 6-12 hrs (no vomiting?); Lasts 24-48 hrs; reheated meats and gravies
What is the most important therapeutic measure in patients with diarrhea and how is it best accomplished?
Rehydration - oral is preferred method but only if tolerated
What organism is hemolytic uremic syndrome associated with?
EHEC infections:
may be triggered by use of Loperamide or antibiotics with EHEC infection

Associated with undercooked hamburger meat, raw milk, lake water and Apple cider
Discuss the concern with anti-peristaltic agents and when they should not be used in patients with diarrhea.
They should not be given when a patient has Fever, bloody diarrhea or children
Define diarrhea, inflammatory diarrhea, noninflammatory diarrhea, and acute and chronic diarrhea.
Diarrhea - Loose or watery stools >3/day or increased volume

Inflammatory diarrhea - Colic tissue damage

Noninflammatory - watery, nonbloody
Discuss the areas of focus in the history of a patient presenting with diarrhea.
Onset, duration
Stress related
Nocturnal diarrhea - Diabetic neuropathy
Frequency - fluid rehydration
Discuss the areas of focus in the physical of a patient presenting with diarrhea.
General Appearance - hydration, mental status

Vital signs

Abd exam - peritoneal pain?

Rectal - fistulas, fecal impaction
List the top 3 causes of inflammatory diarrhea due to bacterial tissue invasion.
1-3 days onset (similar to ETEC)

Salmonella - Food borne eggs, poultry, beef, veggies, fruit

Shigella - human to human

Campylobacter - Chicken (guillain barre syndrome)
List 2 causes of cytotoxin-induced inflammatory diarrhea.
EHEC - Shiga-like toxin attacks intestinal endothelial cells (beef, unpasteurized juice)

C diff - within 2 mos of Antibiotics

Vibrio Parahemolyticus - shell fish
List the causes of noninflammatory diarrhea due to food poisoning from a preformed enterotoxin.
S. Aureus - (1-6 hr incubation) prominent vomiting, lasts 24-48 hrs, Mayonnaise, creams/custards, meats

B Cereus - Emetic onset 1-6 hrs, Diarrhea onset 8-14, Last for 12-24 hrs. Rice and starches

C. perfringens - Diarrhea after 6-12 hrs (no vomiting?); Lasts 24-48 hrs; reheated meats and gravies
What is the most important therapeutic measure in patients with diarrhea and how is it best accomplished?
Rehydration - oral is preferred method but only if tolerated
What organism is hemolytic uremic syndrome associated with?
EHEC infections:
may be triggered by use of Loperamide or antibiotics with EHEC infection

Associated with undercooked hamburger meat, raw milk, lake water and Apple cider
Discuss the concern with anti-peristaltic agents and when they should not be used in patients with diarrhea.
They should not be given when a patient has Fever, bloody diarrhea or children
Differentiate between heat cramps, heat exhaustion, and heat stroke.
Heat cramps - Cramping of muscles due to dilutional hyponatremia.

Heat Exhaustion - dizziness, N/V, with profuse sweating. No mental status changes.

Heat Stroke - hyperpyrexia, CNS dysfunction, anhidrosis.
What type of test is used to assess IV with nominal information and DV that has nominal information
Chi squared
Assessing data that has the IV with measurement data and DV with measurement data?
Pearson correlation
IV nominal data and DV measurement data?
ANOVA - for more than 2 variables

T-test - for 2 variables
IV measurement data and DV measurement data
Spearman Correlation