Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
|
LDL Goal
|
CHD or equivalent (diabetes ) = <100
2+ risk factors = <130 0-1 risk factor = <160 |
|
|
Total Cholesterol goal
|
<200
|
|
|
HDL
|
<40 low
>60 high |
|
|
Triglycerides goal
|
<150
|
|
|
SEcondary causes of hyperlipidemia
|
diabetes
hypothyroidism renal failure |
|
|
Statins mechanism of action
|
inhibit HMG-CoA reductase - inhiit cholesterol synthesis in liver
|
|
|
Bile Acid Sequestrant MOA
|
nonabsorbably anion exchange chloride ions for bile acits
|
|
|
Statin Effects on lipids
|
decrease TC, LDL, TG
increase HDL |
|
|
Bile Acids effects on lipids
|
Decrease TC, LDL
Slightly increase HDL |
|
|
Fibrates effects on Lipids
|
Decrease Triglycerides*
Decrease LDL, increase HDL |
|
|
Niacin effects on lipids
|
Decrease TG*
Decrease LDL, increase HDL |
|
|
Fibrates Mechanism of action
|
reduce triglycerides
|
|
|
Zetia MOA
|
inhibits intestinal absorption of dietary and biliary cholesterol
|
|
|
STatins adverse effects
|
headache, muscle aches, rhabdomyolysis, increased LFTs
|
|
|
Bile Acids adverse effects
|
GI upset, consipation
|
|
|
Fibrates Adverse effects
|
Dyspepsia, gallstones, myopathy
|
|
|
Niacin Adverse effects
|
Flushing, hyperglycemia, hyperuricemia
|
|
|
Zetia adverse effects
|
headache, ab pain, fatigue
|
|
|
Lipitor Generic
|
Atorvastatin Brand
|
|
|
Lescol Generic
|
Fluvastatin Brand
|
|
|
Mevacor Generic
|
Lovastatin Brand
|
|
|
Pravachol generic
|
Pravastatin brand
|
|
|
Crestor Generic
|
Rosuvastatin Brand
|
|
|
Zocor Generic
|
Simvastatin brand
|
|
|
Tricor Generic
|
Fenofibrate Brand
|
|
|
Lopid Generic
|
Gemfibrozil Brand
|
