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10 Cards in this Set

  • Front
  • Back

Physiology

Study of the physical functions of living organisms

Four Primary types of Cells

Epithelial Cells- barrier function, skin cells, endothelial cells


Connective cells- connective and anchor, bone, blood cells


Nerve cells- communication, neuron


Muscle cells- generate force, skeletal muscle cell, cardiac muscle cell

Flood of Fluids through Body Compartments

Nutrients: plasma > interstitial fluid > extracellular fluid > intracellular fluid



Wastes: intracellular fluid > extracellular fluid > interstitial fluid > plasma

Herders on Hasselbalch Equation

pH= pKa + log (A-)/(HA)

Components of Proteins

-amino acids arranged in one long chain


-side chain gives the shape (R group)


-R group can tell us the function


-central alpha connection connects R group to carboxylgroup and amino group


-linked amino acids for peptide bonds

Structural Levels of Proteins

1°- linear chain, order of amino acids


2°- alpha helix, and beta sheet connected by loop conformation


3°- fully folded, 3D functional characteristics


4°- multiple tertiary protein assembled together

Factors determining protein shape

-Hydrogen bonds to side chains


-Ionic bonds to side chains


-Van Der Waal's forces (hydrophobic regions)


-covalent linking of side chains (disulfide bonds)


-denaturing agents (acetic acid, ethanol, formaldehyde)- disrupt protein structure

Specificity

Selectivity of binding site

Affinity

Strength with which ligand binds to its binding site

What determines Chemical Reaction rates?

-reactant concentration


-energy of activation


-pH


-temperature


-presence of catalyst