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14 Cards in this Set
- Front
- Back
What are leukocytes? |
- White blood cells |
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What is an antigen? |
- Anything that has the potential to be recognized by the immune system. |
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What is a foreign antigen? |
- Anything from the outside |
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What is an auto-antigen? |
- Anything that is from self |
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What is the purpose of antigen uptake? |
- Clearance of pathogens (innate response) |
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What happened 500 million years ago that was the beginning of the adaptive immune response? |
- Phagocytes evolved to keep remnants of pathogens and display these to other cells of the immune system. |
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Where did the adaptive immune response evolve from? |
- Jawed fishes |
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What does MHC-I present? |
- Endogenous (intra-cellular) antigens |
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What does MHC-II present? |
- Exogenous (extra-cellular) antigen |
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What is displayed on MHC? |
- Peptides generated from protein antigens |
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What happens after the MHC/peptide complex is formed? |
- It can then be surveyed by antigen-specific t-cells |
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Describe MHC-I processing |
- Intracellular (virus) |
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Describe MHC-II antigen processing |
- Phagocytosis of exogenous antigen |
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What are peptides? |
- Fragments of protein antigen that are displayed by MHC-I and MHC-II |