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28 Cards in this Set
- Front
- Back
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Building blocks of life |
Cell |
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Normally confined to a narrow range of function and structure |
Cell adaptation |
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Steady state |
Homeostasis |
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Cellular adaptation is controlled by |
Complex molecular mechanisms |
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Factors that determine whether injury or death will occur |
... |
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Cause of cell injury and death |
PIGIIN |
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Primary targets of cell death and injury |
... |
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Mechanisms of cell death and injury |
.... |
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Cell injury |
Fatty change, cell swelling, inusions |
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Pigments |
Carbon hemosidirin bilirubin lipofuchsin melanin |
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Types of cellular adaptation |
.... |
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Physiologic atrophy |
Decreased use |
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Pathologic atrophy |
Diminished blood supply, denervation, nutritional deficiencies |
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Hypertrophy is ussually seen in cells that |
Are not capable of dividing |
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Physiologic hyperplasia |
Increased production of local growth hormone receptors |
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Pathologic hyperplasia |
Stimulation of growth hormone Neoplasms |
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Most common metaplasia |
Comumnar to squamous |
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Limits of adaptive response is exceeded cell is exposed to injurious agent ir stress |
Cell injury |
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Reversible cell injury |
Vacuolization and cellular swelling Fatty change |
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Irreversible cell injury |
Enzymatic degradation autolysis Protein degradation Karryolysis pyknotic karryohexis |
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Chronic cell injury |
Cytoskelton and mitoxhondria |
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Death of cell occurs in two ways |
Apoptosis and necrosis |
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Patterns of necrosis |
5 |
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Cytoskeletal changes |
Mallory body Neurofibrillary tangles Lewy body |
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Morphology of apoptosis |
.... |
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Inflammatory reaction: necrosis or apoptosis |
Necrosis |
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Inhibitory of apoptosis |
Bcl-2 |
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Stimulatory of apoptosis |
Bax |
