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47 Cards in this Set
- Front
- Back
CD marker of NK cells
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CD56
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B cells are derived in these 2 tissues
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Bone marrow and GALT
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Main function of B cells
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Immunoglobulin production
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CD markers of B cells
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CD9,19 and others
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Primary (or central) lymphatic organs
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Bone marrow
Thymus GALT |
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Secondary (or peripheral) lymphatic organs
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Lymph nodes
Tonsils Spleen |
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Accumulation of the lymphatic tissue which does not have capsule, which is located at the GI (alimentary) canal, respiratory passages and genitourinary tract (lamina propria)
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MALT (Mucosa-associated lymphatic tissue)
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Large numbers of plasma cells in MALT indicates
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Immunoglobulin production
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Large numbers of eosinophils in MALT indicates
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chronic inflammation and hypersensitivity reaction
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Peyer's patches, tonsils and appendix are this type of tissue
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MALT
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Diffuse lymphoid tissue in the
wall of GI, GU and RT forms (no germinal centers) |
Lymphoid Nodules or Lymphatic Follicles (Primary)
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This has a germinal center (GC), which consists of lymphocyes that have recognized Ag’s and come back to primary follicles with proliferation
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Secondary lymphatic nodule
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Light center of the lymphatic nodule consists of
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Euchromatin
(follicular dendritic cells and macrophages increased after immune response) |
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MZ (mantle zone or corona) of the lymphatic nodule consists of
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small lymphocytes
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Forms the lymphatic tissue ring around oropharynx
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Tonsils
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Types of tonsils
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Pharyngeal, palatine and lingual
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Tonsils do not have _____ vessels, but they do have lymphatic drainage
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afferent
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Tonsil epithelium
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Stratified squamous
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The tonsils are covered by squamous epithelium which dips into the connective tissue, which forms
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Tonsillar crypts
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Peyer’s patches are located in the
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Ileum
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Peyer's patches consist of aggregations of lymphatic nodules containing both of these cells
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T and B lymphocytes
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This layer in the intestines is densely infiltrated by lymphocytes and contains multiple follicles
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Lamina propria
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Encapsulated organs located along the pathway of lymphatic vessels and serve as filter for lymph
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Lymph Nodes
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Superficial cortex of the lymph nodes consist of
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Primary and secondary nodules
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Deep cortex (paracortex) of the lymph nodes consist these cells
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T lymphocytes
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Medullary cords of the lymph nodes consist of
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B lymphocytes
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Capsule and trabeculae of the lymph node consist of
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Dense connective tissue
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Lymph nodules of the lymph nodes consist of
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B lymphocytes
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Serves as the entrance to the lymph node for circulating lymphocytes
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HEV (high endothelial venules; 90% of lymphocytes enter through this route)
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Circulating lymphocytes enter this layer of the lymph node (via HEV)
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Deep cortex
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Put in order of flow in the lymph node : medullary sinuses; trabecular sinuses; subcapsular sinuses
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1. Subcapsular
2. Trabecular 3. Medullary |
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Reticular cells of the lymph node synthesize and secrete this type of collagen
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Type III
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Location of follicular dendritic cells
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Germinal centers of the lymph nodes (Distributed between B-cells)
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Function of follicular dendritic cells
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Bind to Ab-Ag complexes; they are not APC's
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Cortex of the thymus consist of closely packed
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T lymphocytes
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Dense accumulation of the
lymphcytes surrounding blood vessels in the spleen |
White pulp (PALS)
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Layers of the epidermis that Langerhans' cells are only found
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The middle layers of epidermis
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Lymphatic and hematopoietic tissue cells possess these unique cell surface molecules named by an international system that relates them at different stages of their differentiation
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CD molecules (cluster of differentiation)
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CD2
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Clinical marker for T cells
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CD molecule that's elevated in chronic lymphocytic leukemia
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CD5
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Clinical marker for T-cell leukemia (CD molecule)
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CD7
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Common marker (CD molecule) for acute lymphoblastic leuemia
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CD10
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Clinical marker (CD molecule) for all stages of B-cell development
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CD19
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CD34
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Clinical marker for pluripotential stem cells in bone marrow
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CD38
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Marker for T-cell activation
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CD56 and CD94
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Clinical Marker for NK cells
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Helper T cells that synthesize IL-2, IFN-gamma and TNF-alpha are called
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Th1 cells
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