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12 Cards in this Set
- Front
- Back
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What are three unique cells of the liver?
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Hepatocytes
ito cells kupffer cells |
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what are hepatocytes
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liver cells that perform most major functions of liver, they have microvilli on sinusoidal side to increase absorption, secrete bile from one surface into the canaliculi, secrete lymph from another into space of disse
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what are ito cells?
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ito cells store fat and vitamin A
they sit between hepatocytes in space of disse Also called stellate cells |
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what are kuppfer cells?
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they are liver monocytes/macrophages that remove debris (old blood cells) they form part of the lining of the sinusoid
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Describe blood flow in liver
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blood from hepatic portal vein and hepatic artery flows from portal areas towards the central vein through the sinusoids.
The central veins coalesce to allow blood to leave trhough the hepatic vein |
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describe the flow of bile in liver
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bile is secreted by hepatocytes into canliculi between cells (no into the sinusoids), collects in the portal area bile ducts which coalesce to allow bile to leave the liver through the hepatic bile duct
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describe the flow of lymph in the liver
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lymph is secreted by hepatocytes into the space of disse between the endothelial cells anc hepatocytes. it flows towards the portal area lymph vessels which coalesce
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hepatic sinusioids have which type of enodthelial
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discontinuous fenestrated ???
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what are the functions of bile?
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excretion of cholestreol phospholipids, bile salts conjugated bilirubin and electrolytes
contribuest to fat absorption in the intestinal lumen transport IgA to the intestinal mucosa excrestion of metabolic products of drugs and toxins processed by hepatocytes production of bile acids that inhibit growth of bacterial i the small intestine |
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does transport of bile from hepatocyte to canaliculus require energy?
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yes it is an is an ATP dependent process!
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what are the functions of the gallbladder?
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concentrates bile up to 10x and stores bile between meals
stores up to 50 ml release bile due by muscular contraction in response to cholecystokinin and neurol stimulation regulation of hydrostatic pressure in the billiary tract |
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Describe the histology of the gall bladder:
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pear shaped musclular sac
covered by visceral peritoneum lacks submucosa dn muscalaris mucosa numerous mucosal folds connected to viscerl surface of the liver by loose connective tissue surface compose of simple columnar epithelium |
