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14 Cards in this Set

  • Front
  • Back
ECM
95% is cartilage
5% is Ground substance - GAGS
CARTILAGE IS AVASCULAR, supplied by perichondrium
Hyaline Cartilage
Nose, tracheal rings, costal cartilages, bone surfaces, fetal skeleton, epiphyseal growth 
Type II Cartilage 
-Have appositional and interstitial growth 
-bad regeneration - leaves scar 
Function:
cushion, structure, shock absorber
Nose, tracheal rings, costal cartilages, bone surfaces, fetal skeleton, epiphyseal growth
Type II Cartilage
-Have appositional and interstitial growth
-bad regeneration - leaves scar
Function:
cushion, structure, shock absorber
Perichondrium
Is connective tissue covering,
Outer Layer -containing type 1 collagen, fibroblasts and BV
Inner Layer - source of chondroblasts 
NO Perichondrium at joints
Is connective tissue covering,
Outer Layer -containing type 1 collagen, fibroblasts and BV
Inner Layer - source of chondroblasts
NO Perichondrium at joints
Chondrocytes
Are matured chondroblasts located in lucanue of cartilage. Mitotic division leads to group of 4-8 chondrocyte reffered to Isogenous groups or cell nest.
Are matured chondroblasts located in lucanue of cartilage. Mitotic division leads to group of 4-8 chondrocyte reffered to Isogenous groups or cell nest.
Capsular matrix - (matrix adjacent to the chondrocyte) is poor in collagen but rich in glycosaminoglycans
Territorial matrix- matrix found around Isogenous groups.
Inter territorial matrix – matrix inbetween isogenous groups
Matrix
Sulphated groups present in GAGs, make it hydrophilic, enabling easy diffusion of nutrition to the cells.
Presence of proteoglycans provide immense strength to the matrix
so that cartilage can function as
a model for bone formation.
Appositional Growth
Appositional growth occurs from chondrogenic cells in the perichondrium differentiating into chondroblasts, forming a new layer of cartilage around the periphery of the existing cartilage.
Appositional growth occurs from chondrogenic cells in the perichondrium differentiating into chondroblasts, forming a new layer of cartilage around the periphery of the existing cartilage.
Interstitial Growth
Interstitial growth (growth from within) occurs only in young cartilage from cell divisions within the cartilage.
This process increases the length of the cartilage
Interstitial growth (growth from within) occurs only in young cartilage from cell divisions within the cartilage.
This process increases the length of the cartilage
Throxine and Testosterone
Increases Interstitial Growth
Hydrocortisone and Estradiol
Decrease Interstitial growth
Articular cartilage
Hyaline cartilage at joints which do not contain perichondrium.
Hyaline cartilage at joints which do not contain perichondrium.
Elastic Cartilage
Ear, auditry canal, ear tube, epiglottis 
Type II collagen and ELASTIC FIBERS
NEVER CALCIFIES 
Matrix identical to hyaline, but contains elastic fibers 
Support and flexibility
Ear, auditry canal, ear tube, epiglottis
Type II collagen and ELASTIC FIBERS
NEVER CALCIFIES
Matrix identical to hyaline, but contains elastic fibers
Support and flexibility
Fibrocartilage
Invertebral disc (annulus fibrosis), attachment of ligament to bone, articular discs, pubic symphysis 
TYPE I Collagen but does contain Type 2
GAGS - mainly chondroiti
ONLY INTERSITIAL GROWTH - NO PERICHONDRIUM
SUPPORT and tensile strength
Invertebral disc (annulus fibrosis), attachment of ligament to bone, articular discs, pubic symphysis
TYPE I Collagen but does contain Type 2
GAGS - mainly chondroiti
ONLY INTERSITIAL GROWTH - NO PERICHONDRIUM
SUPPORT and tensile strength
Cartilages