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48 Cards in this Set
- Front
- Back
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Connective tissue divisions? |
CT proper CT with special properties Supporting CT |
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CT proper, types? |
Loose (areolar) Dense - regular/irregular |
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CT with special properties |
Adipose tissue Mesenchymal CT Hematopoetic tissue and blood |
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Supporting CT |
Cartilage Bone |
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CT is composed of? |
Cells ECM; ground substance and fiber |
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Function of CT |
Support Medium for exchange Defense, protection, repair Storage of fat |
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Categories for cells in CT? |
Fixed (resident) Transient (immigrant) |
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Fixed cells |
Fibroblast, fibrocyte Adipose Pericytes Mast cells Macrophages |
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Transient/immigrant cells |
Lymphocytes Monocytes Neutrophils Eosinophils Basophils Plasma cells Plasma cells |
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How will transient cells move? |
From bone marrow -> blood stream. Recieves stimuli, leaves blood stream -> migrate to CT |
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Fibroblast |
Synthesis of ECM (degrading enzymes) Abundant in CT Resident, but can move Wound healing |
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Active fibroblast can become a...? |
Quiescent fibrocyte |
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Difference between a fibroblast and fibrocyte? |
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-blast vs -cyte? |
Blast = precursor |
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Myofibroblast |
Modified fibroblast Similar to smooth muscle cells |
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Pericytes |
Undifferentiated mesenchymal cells Surrounds endothelial cells of capillaries May function in contraction |
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Adipose cells |
Derived from mesenchymal cells Synthesis and storage of triglycerides Produce ADIPOKINES |
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Two types of adipose? |
Unicolar fat cells - form white adipose tissue Multilocular fat cells - form brown adipose tissue |
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Development of fat cell |
Mesenchymal cell Accumilation and coalescense of lipids Surrounded by basal lamina |
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WAT function? |
Synthesis, storage and release of triglycerides Release of hormones, cytokines Protection Body shape |
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What is adipokine? |
Cytokine (cell signaling protein) secreted by adipose tissue |
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Function of adipokines |
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Difference in structure, brown and white adipose? |
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BAT function? |
Neonates Heat production, thermogenin |
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Mast cells, arise from? |
Bone marrow stem cell MYELOID STEM CELL |
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Mast cells function in? |
Mediating inflammatory responses and immediate hypersensitivity reactions |
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Mast cells granules contain? |
Histamine, heparin, neutral proteases (tryptase) PRIMARY MEDIATORS |
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The two population of mast cells? |
Connective tissue mast cells Muscosal mast cells |
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CTMCs and T-cells |
not dependent |
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MMCs and T-cells? |
Dependent!! |
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Mast cells initiate? |
Immediate hypersensitivity reaction Aka anaphylactic reaction |
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Mast cells have what receptors for what? |
Fc receptors IgE |
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Activation and degranultion |
Formation of antibodies, sensitizing Receptor coupling factors Primary mediators from granules Synthesis and release of secondary mediators cAMP Ca+ released Degranulation |
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Release from mast cells sequence |
1. Granule mediators 2. Lipid mediators 3. Cytokines |
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Macrophage, two groups? |
Phagocytes Antigen-presenting |
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Monocyte develop in bone marrow and circulate to blood. In CT they become what? |
Macrophage |
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How does macrophages fight foreign substances? |
Phagocytose |
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Plasma cell, content? |
RER, cisternae containing Ig Basophilic Spherical nucleus Euchromatim and heterochromatin in cell |
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Leukocytes types |
Monocyte Neutrophils Eosinophils Basophils Lymphocytes |
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Embryonic tissue |
Mesenchymal tissue + mucous tissue. |
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Mucous tissue/Warton jelly |
Jelly-like, hyaluronic acid, type 1 and 3 collagen, fibroblast |
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Loose CT |
Lies under epithelia of digestive and respiratory = immune cells Ground substance Fibroblast, adipose cells, macrophages, mast cells Collagen, reticular, elastic fibres Edema |
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Dense connective tissue |
Abundance of fibers, fewer cells |
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Dense irregular CT |
Random bundles of collagen Fibroblast Little ground substance |
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Dense regular collagenous CT |
Paralell collagen Tendon, ligaments |
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Dense regular elastic CT |
Few collagen Fibroblasts Large blood vessels, ligamenta flava |
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Reticular tissue |
Type 3 collagen Fibroblasts and macrophages |
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WAT |
Blood vessels Plasma membrane of unilocular adipose cells contain reseptors for insulin, growth hormone, etc Metabolism Macrophages, mast cells, fibroblast |
