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13 Cards in this Set

  • Front
  • Back

Heparin MOA

Anticoagulant.



Potentiates the activity of antithrombin III (naturally occurring anticoagulant), which then causes inhibition of multiple coagulant factors.

Heparin INDICATIONS

STEMI in conjunction with fibrinolytic therapy.

Heparin CONTRAS

Known severe Ax.



Age 75yrs and older. Increased risk of intracerebral haemorrhage.


(In combination with fibrinolytic therapy).

Heparin CAUTIONS

Clinically significant bleeding. Increases bleeding.



At risk of bleeding. Any cautions or contras present in checklist, seek clinical advice.



Pregnancy.

Heparin IN PREGNANCY

Safety not demonstrated.



Likely of STEMI in pregnancy is low, seek clinical advice.



May be administered if breastfeeding, stop and contact LMC.


Heparin DOSE

5000 units

Heparin ADMINISTRATION

Dilute to a total volume of 10ml using 0.9% NaCl.



Administer IV over 1-2 minutes.

Heparin ADVERSE EFFECTS

Increased bleeding.

Heparin ONSET

5-15 minutes

Heparin DURATION

2-4hrs

Heparin PREPARATION

Ampoule containing 5000 units.

Heparin PHARMACOKINETICS

Unclear how it is cleared.

Heparin INTERACTIONS

Risk of bleeding increased of patient is taking an anticoagulant.