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21 Cards in this Set
- Front
- Back
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The coagulation Common pathway consists of:
A.) factors II, VII, IX, and XI B.) XII, XI, XIII and IV C.) III, vWF, Ca2+, and prothrombin D.) II, V, and X |
D.) II, V, and X
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Tissue thromboplastin (tissue factor) activates the coagulation system. The primary factor that tissue thromboplastin activates is:
A.) I B.) XIII C.) VII D.) VIII E.) XII |
C.) VII
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von Willebrand's factor is:
A.) LMW and called VIIIC:Ag B.) HMW and called VIIIR:Rco C.) HMW and called VIIIC D.) LMW and called VIIIR:Ag |
B.) HMW and called VIIIR:Rco
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The Vitamin K dependent factors are:
A.) II, XII, IX, XIII, protein C, thrombomodulin B.) VII, V, IX, X, protein C, protein S C.) I, VI, IX, X, protein C, protein S D.) II, VII, IX, X, protein C, protein S |
D.) II, VII, IX, X, protein C, protein S
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vonWillebrand factor is the carrier protein for coagulation factor:
A.) VII B.) V C.) VIII D.) IX |
C.) VIII
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For the majority of coagulation proteins, an acitivity level of ____% is all that is necessary for hemostasis.
A.) 10-15 B.) 25-30 C.) 45-55 D.) 75-85 |
B.) 25-30
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Protein C along with it's Cofactor Protein S cleave factor:
A.) XIIIa B.) IXa C.) Va D.) VIIa |
C.) Va, causing anticoagulation
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Protein C depends upon two of the following in order to become activated.
A.) Thrombomodulin B.) Thromboxane A2 C.) Factor Xa D.) Factor IIa (thrombin) E.) Prostacyclin F.) alpha-2 antitrypsin |
A.) and C.) Thrombomodulin and Factor IIa (thrombin)
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Converts fibrinogen to fibrin
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thrombin
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Crosslinks fibrin multimers to form a stabilized clot
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factor XIII
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Factor Xa and its cofactor ____convert prothrombin to thrombin
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factor Va
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Antihemophilia A factor
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factor VIII
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Antihemophilia B factor
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factor IX
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Which of the follwoing is an example of an acquired platelet disorder?
A.) Uremia B.) Bernard-Soulier syndrome C.) Storage pool deficit D.) vW disease E.) May-Hegglin anomaly |
A.) Uremia
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Thrombotic thrombocytopenia purpura (TTP) quantitative or qualitative
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quantitative
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Uremia
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qualitative
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Glanzman's Thrombasthenia
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qualitative
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aplastic anemia
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quantitative
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immune thrombocytopenia purpura (ITP)
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quantitivative
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A 3 year old presents with severe thrombocytopenia following a bout of bloody diarrhea caused by E. coli 0157:H7. The most likely disorder is:
A.) cirrhosis B.) lupus erythematosis C.) vonWillebrand's disease D.) TTP E.) ITP |
D.) TTP
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This disease has multiple presentations: In children more boys than girls are affected, in adults more women than men are affected. In children the best treatment is no treatment while in adults, corticosteroids are often effective, RhIg may also be utilized in some adults. The disease that best fits this description is:
F.) DIC G.) ITP H.) HUS I.) TTP J.) HITT |
G.) ITP
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