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19 Cards in this Set
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Lymphoblast Nucleoli in the nucleus = blast cell which should never be present in circulation. |
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Plasma Cells Would rarely see plasma cells in circulation otherwise. Sorta look like lymphocytes but nucleus is eccentric (to one side of cytoplasm) and there is a lot of cytoplasma. not as common as lymphocytic tumours |
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Mast Cell Leukemia |
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Metestrus - see WBC not RBC. Non-cornified |
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Estrus - all cornified, very faded nucleus, do not see RBC or WBC in background |
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Proestrus - RBCs high initially, increasing numbers of cornified cells reaching nearly 100% by the end |
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Anaplasma phagocytophilium -affects dogs cats, horses and people -Deer tick transmitted Gram negative bacteria that parasitizes neutrophils -Snap 4DX detects antibodies -PCR confirm presence -Clinical signs: fever, leathery, inappetence, vomiting, diarrhea and lameness -Tx: doxycycline |
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Basophilic Stippling -RNA remnants that stain blue on Wright’s stain. Common in young ruminants with a regenerative anemia. |
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Toxic Change -Doehle bodies -Cytoplasmic granulation -Cytoplasmic basophilia -Nuclear immaturity |
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Mycoplasma hemofelis -arthropod transmitted -Clinically: depressed, febrile, pale, anorexic +/- jaundiced -makes the RBC less deformable so the RBCs are removed by macrophages in the spleen -Tx: doxycycline, immune suppression with prednisone, blood transfusion if critical |
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Iron deficiency -non-regenerative anemia -microcytic, hypochro |
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Acanthocytes -are associated with a common splenic tumor called hemangiosarcoma -RBCs stagnate in cavernous spaces within the tumor, resulting in shifts of lipids in the RBC membrane and the blood |
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Leukemoid reaction -seen in severe infections e.g. pyometra -very elevated WBCs that are mainly neutrophils |
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Toxic Change -neutrophils mature abnormally due to intense neutrophil production and shortened maturation time -Usually in response to inflammation |
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Ghost RBCs and free hemoglobin
-seen with intravascular hemolysis |
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Reticulocytes In cats, count only aggregate, not punctate reticulocytes aggregate change into punctate, normal cats can have up to 10% b/c they stay around for about 10 days |
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Polychromatophils and Howell-Jolly Bodies -Howell-Jolly bodies nuclear remnant, cells being produce quickly, more prone to mistakes and some of nucleus gets left behind -Blue in reticulocytes is ribosomal components |
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Eccentrocytes - RBC membrane is oxidized. Visible as an eccentric crescent shaped clearing in a RBC |
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Metarubricyte -one stage before polychromatophil - nuclear material is so dense it is called pyknotic |
