Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
aplastic anemia is ___penia caused by ___.
|
pan cyto
defective hematopoiesis |
|
2 causes of defective hematopoiesis in AA
|
stem cell failure due to intrinsic damage
autoimmunity against stem cells |
|
3 scenarios for AA
|
acquired
idiopathic congenital |
|
most common scenario for AA is
|
idiopathic
|
|
4 causes of acquired AA
|
drugs
radiation chemicals viral |
|
5 drugs which cause AA
|
chemotherapy
sulfa choramphenicol indomethacin gold |
|
3 chemicals which cause AA
|
benzene
insecticides hair dyes |
|
virus which causes AA
|
HAV
|
|
anemia in AA is ___cytic and ___chromic
|
normo
normo |
|
retic count in AA is ___
|
<1%
|
|
3 criteria for AA
|
neutrophils < 500/uL
platelets < 20,000/uL retics < 20,000/uL (<1%) |
|
___ of the criteria are needed to diagnose AA
|
at least 2
|
|
"super severe" AA is defined by ___
|
neutrophils < 200/uL
|
|
3 parts of supportive tx for AA
|
RBC transfusion
platelet transfusion aggressive antibiotics |
|
2 parts of definitive tx for AA
|
immunosuppression
allogeneic SC transplant |
|
2 kinds of immunosuppressive tx for AA
|
anti thymocytic globulin
cyclosporine |