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12 Cards in this Set
- Front
- Back
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Myelodysplasia |
Risk: sickle cell patients who are infected with parvovirus B19 parvovirus B19, EBV, HIV, CMV, and HCV) chloramphenicol, anti-epileptics, Fanconi anemia B12 and folate deficiency Symptoms : anemia, thrombocytopenia, leukopenia Ix, BM biopsy Mx, Withdrawal of causative agent RBC transfusion platelet transfusion Curative - bone marrow transplant for healthy patients under 50 Medical therapy – immunosuppressive agents for over 50 or those with comorbiditiesantithymocyte globulin plus cyclosporine |
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Condition associated with AML |
Down Fanconi Anaemia Ataxia telangiectasia Myeloproliferative syndrome |
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Immunoglobulins A deficiency |
IgA deficiency develop severe respiratory and gastrointestinal tract infections Respiratory infection |
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Ataxia telangiectasia |
rare inherited childhood neurological disorder that affects the part of the brain that controls motor movement (intended movement of muscles) and speech. |
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How to differentiate hemolytic anaemia from anaemia of chronic disease |
Low haptoglobin in hemolytic anaemia |
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Most sensitive & cost-effective initial test for hemochromatosis |
Transferrin saturation - increased |
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Most common cardiac manifestation of hemochromatosis |
CHF |
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Evaluation of IDA in 50+ and no other cause found including negative occult blood in stool and negative FOBT |
Go for colonoscopy even FOBT negative Screening of colon CA recommended 50 with occult blood |
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Hereditary hemochromatosis |
Autosomal recessive Ane usually done after the age of 18y |
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Prognosis of multiple myeloma |
Prognosis is poor with low albumin and high beta 2 micro globulin |
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Aplastic anaemia causes |
NSIADs Salphonamides Gold Antiepileptics - carbamazepin, phenytoin, valproate Chloramphenicol Parvovirus B19 HIV HBV, HCV |
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Most common cause of death in hemochromatosis |
Liver disease |
