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73 Cards in this Set
- Front
- Back
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Describe wormd in the blood |
Athanasius Kircher |
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Discovery of erythrocytes |
Swammerdam |
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Describe human erythrocytes |
Van Leuwenhoek |
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Year when platelets were described |
1842 |
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PMN distinguished from other leukocytes |
Wharton Jones (1846) |
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First complete classification of leukocytes |
Ehrlich 1879 |
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Development of wrights stain |
James Homer Wright 1902 |
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1920 |
Hematology was considered a separate science from clinical pathology |
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dys |
Abnormal |
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Emia |
In the blood |
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Myelo |
Marrow |
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Normo |
Normal |
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Like |
Oid |
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FBC |
Full Blood Count |
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Fl |
Femtoliter |
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Hb |
Hemoglobin concentration |
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Hct |
Hematocrit |
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MCH |
Mean Cell Hemoglobin |
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MCV |
Mean Cell Volume |
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MCHC |
Mean Cell Hemoglobin Concentration |
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PG |
Picogram |
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Life sustaining fluid which circulates thru the heart and blood vessels |
Blood It carries oxygen and nutrients to the tissues and waste products to the lungs, liver, and kidney where they can be removed from the body. |
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Blood Composition |
Formed elements Plasma |
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Formed elements |
Erythrocytes Leukocytes Thrombocytes |
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Liquid portion of unclotted blood |
Plasma |
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The fluid that remains after coagulation has occurred and clot has formed |
Serum |
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Percentage of water in plasma |
90% |
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Other components of plasma aside from water |
Proteins Enzymes Hormones Lipids Salts |
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Normal color of plasma |
Hazy and pale yellow |
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Normal appearance of serum |
Clear and straw colored |
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Plasma contains... |
Fibrinogen which is an anticoagulant factor |
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5 parameters of CBC |
HgB Hct WBC RBC Differential count |
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Increase WBC count could indicate... |
Leukocytosis Leukopenia |
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Used for blood indices |
Femtoliter |
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Determine the type of anemia |
MCH MCV MCHC |
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Measures the amount of packed red cells |
Hct |
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Used for blood indices |
Picogram Femtoliter |
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Tube used for serum |
Plain tube Red tap |
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Coagulation factors are written in what? |
Roman Numerals |
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Factor 1 |
Fibrinogen |
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Factors present in serum which are completely consumed in the coagulation process |
FI FV FVIII FXIII |
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Portion of factor II thst remains in serum |
Residual Prothrombin |
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Not completely consumed. >80% is consumed and <20% remains in serum |
FII |
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Buffy coat components |
Leukocytes Platelets <1% of total blood |
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55% of total blood |
Plasma |
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45% of the total blood |
Erythrocytes |
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Stuart-Prower Factor |
Factor X |
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Fibrin-Stabilizing Factor |
Factor XIII |
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Factor V |
Proaccelerin |
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Factor II |
Prothrombin |
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In vitro, blood coagulates in... |
5-10 mins |
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Blood is .... thicker than water |
3.5-4.5 times |
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Blood makes up how many percent of the total body component |
6-8% or 60-80ml/kg |
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Total Body Volume |
Adult male: 5-6L Adult female: 4-5L Newborn: 250-350 mL |
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Thickness or stickness of blood |
Blood viscosity |
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Blood viscosity |
Resistance of blood to flow |
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Viscosity of blood is ... times more than that of water |
5 |
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Blood Viscosity depends on... |
RBCs Plasma proteins |
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General characteristics of blood |
1. In vivo, blood is in fluid; in vitro it coagulates in 5-10 minutes 2. Thick and viscous 3.5-4.5 times thicker than water 3. Makes up 6-8% of the total body component or 60-80ml/kg 4. Approximately 20 gms solid per 100 ml 5. Total Blood Volume AM: 5-6L AF: 4-5L Newborn: 250-350 mL |
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Measure of the acidity or basicity of an aqueous solution |
pH |
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The negative decimal logarithm of H concentration |
pH Potential of Hydrogen |
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Normal blood pH |
7.35-7.45 Average of 7.40 Venous blood: 7.35 Arterial blood: 7.45 |
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How is blood pH maintained? |
Excretion of CO2 by the lungs Excretion of H+ or OH by the kidney by the action of buffer system |
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Buffer system |
Hemoglobin Protein Phosphate Carbonate |
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The ratio of the density of a substance to the density of a reference substance |
Blood Specific Gravity |
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Other name for BSG |
Relative density |
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SG depends on... |
RBCs Plasma proteins |
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Number of solutes dissolved in the blood |
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Pigments Arterial blood Venous blood |
Bright red Dark purplish red |
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Pigments in pulmonary arteries and veins |
Hb with O2 : purple Hb without O2: blue |
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Concentration of solutes dissolved in blood |
Osmolality |
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Measurement used for osmolality |
Osmometer MEASUREMENT RANGE: 281-297 milli-osmoles per kilogram (mOsms) |
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Function of Blood |
Respiratory Nutritional Excretory Buffer action Maintenance of constant body temp Transportation of hormones and other endocrine secretion that regulates cell function Body defense mechanism |
