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30 Cards in this Set
- Front
- Back
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Explain all of the layers of the skin and the layers of the epidermis.
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stratum corneum
stratum lucidum stratum granulosum stratum spinosum stratum basale |
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What are the layers and structures and describe what what type of inflammation occurs here? Where do bacterial infections occur? Viral?
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Viral- Epidermis -Molluscum contagiosum, herpes virus, verruca
Appendages- folliculitis - herpesvirus |
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Describe this skin image and what can cause it? Treat?
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Thin walled vesicles, pustular and rupture causing a honey-colored crust around the mouth. Impetigo
Dx: Punch biopsy Org: Staph 50-70%, streptococcal. Just below the stratum corneum. Tx: topical antibiotic, +- oral antibiotic |
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Describe this skin image and what can cause it? Treat?
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Follliculocentric pustules, or dome shaped pustules
Dx: punch biopsy Org: Staph aureus most common Tx: antibacterial soap, top or sys abx |
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Describe this skin image and what can cause it? Treat?
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grouped pustules on an erythematous base following a dermatome.
Dx: Tzanck smear (multinucleated cells and ground glass), Punch biopsy-see multinucleated cells Org: VZV reactivation Tx: acyclovir |
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What is this and describe it? and what causes it?
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Papular vesicle and umbilicating.
Eczema Herpeticum Secondary herpes virus infection on top of a rash. |
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What is this and describe it? What causes it?
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Herpetic Whitlow
Infection of the distal phalanx or toes. Caused by herpes viruses (HSV-1 HSV-2) |
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What are all of the herpesviruses and genomic structure?
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dsDNA linear
HSV-1 HSV-2 VZV CMV EBV HHV-6 HHV-8 |
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What is this and describe it? and what causes it? Treatment and Dx?
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Grouped, flesh colored red umbilicated papules.
Also 1-2mm smal white bumps with a central dimple. Org: Pox virus Dx: punch biopsy Pop: young children, sexually active, T-cell suppression Trans:skin to skin Histology: molluscum (henderson-paterson bodies) Tx: spontaneous in kids. |
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What is this and describe it?
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Verruca vulgaris, caused by HPV
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What is this and what causes it?
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Verruca plantaris and HPV.
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What is this and what causes it?
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Verruca plan and caused by HPV 3 10 28 41
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What is it and what causes it?
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Genital wart, condyloma
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What is this? How would you diagnose? Histology?
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Grouped on right lower back, orange scaly macules, (papule is elevated, so these you cant feel) that coalesce into patches.
Dx: KOH, on histology hyphae and yeast Tinea Versicolor Bug:Pityrosporum orbiculare Tx: systemic or topical antifungal |
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Describe the rash. What do you do to diagnose it? What causes it?
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Scaly rash on back and hand.
Dx: KOH stain, Punch biopsy Org: Dermatophyte, only survive on dead skin. |
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What is going on here? What is it called? What causes it?
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thick crumbling plates of the nail
Dx: KOH (branched hyphae), PAS of nail plate, Culture of nail plate Ddx: psoriasis, lichen planus, eczema, contact dermatitis Diabetes complicatoins, Tx: Most patients not symptomatic, systemic antifungal 12-16 weeks |
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What is this and describe it? and what causes it? Treatment and Dx?
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pruritic papular eruption on wrist. Crusted papules with plaques. some look more pustule
Dx: Scabies - itch mite Circle of hebra: an anatomic circle encompassing the axillae, hands, genital region, elbow flexures Tx: oral ivermectin, permethrin 5% cream |
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What is this and describe it? and what causes it? Treatment and Dx?
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ulcerated, firm plaque with satellite papules
Deep fungal infection. Mariner's wheel - paracoccidiomycosis Other causes: coccidiodomycosis (SW USA), para (SA), Histoplasmosis (Central USA), Blastomycosis (NA) Tx: antifungals |
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albendazole
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Use against enterobius vermicularis, ascaris lumbricoides, hookworms (acylostoma duodenale, necator americanus, strongyloides stercoralis)
decrease glucose absorption |
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praziquantel
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use against cestodes, schistosomes, cysticercosis, clonorchis sinensis
Ca release and paralysis of the organis |
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ivermectin
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opens gated chloride channels, causes increased flux of chloride and paralysis
use against nematodes and arthropods |
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Diethylcarbamazine
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enhances host immune system
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doxycycline
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tetracycline - 30s cidal protein inhibitor,
tox: teratogen, photosensitivity, bone growth, discolored teeth. wolbachia in filarial infections. unique. |
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What infections can you get from lice?
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Rickettsia prowazekii: epidemic typhus
Bartonella quintana: trench fever Borrelia recurrentis: relapsing fever Only from BODY lice |
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What diseases are associated with fleas?
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Rat flea: plauge, murine typhus
Cat/Dog flea: hypersensitivity and dermatitis Tunga penetrans - through feet |
