Groen Licht Toets

Front 1

Propofol

Back 1

M: 10 mg/ml (1%); 20 mg/ml (2%, pomp)

Ind LBW: 1-2,5 mg/kg (K 2-3,5)
Cont TBW: 2-10 mg/kg/h (K 3-15)
Of 10-8-6 regel (30min) TCI Ind 4μg/ml – cont 2,5-3,5
Sedatie 1-2mg/kg/h

Front 2

Thiopental

Back 2

M: 500 mg --> 25mg/ml in 20ml H2O

Ind LBW: 3-5mg/kg (K 2-8; O 4-5)
Onderhoud TBW: 2mg/kg
Werkt zeer snel

Front 3

Midazolam

Back 3

M: 3ml 5 mg/ml; 5x

Ind TBW: 0,1-0,2mg/kg (V=K)
Cont BW: 0,05-0,2mg/kg/h
Premed: 7,5-15 mg PO (K 0,3-0,5mg/kg)
Flumazenil: 0,1-0,5mg iv (K: 10μg/kg, max 1mg)

Front 4

Dexmedetomidine

Back 4

M: 2ml 100 μg/ml; 25x

Oplaad: 0,7bμg/kg in 10-15 min
Cont: 0,2-1,4μg/kg/h
Oplossing in NaCl of Gluc 5%
CI: hypotensie, bradycardie

Front 5

Sevoflurane MAC

Back 5

- 25y 2,6%

- 40y 2,1%

- 80y 1,4%

- met opiaten MAC<1

Front 6

Desflurane MAC

Back 6

- 25y 7,3%

- 45y 6,0%

- 75y 5,2%

- met opiaten MAC<1

Front 7

Etomidaat

Back 7

M: 10ml 2mg/ml
Ind: 0,2mg/kg (K: 0,3-0,5)
Hypnomidate bij soja-allergie
CI: bijnierschors insufficientie

Front 8

Ketamine

Back 8

M: 5ml 5mg/ml-10ml 25mg/ml; 5x
Ind IBW: 1-2mg/kg (K 0.5-1)
Analgesie IBW: 0,25mg/kg – cont 0,1-0,4 mg/kg/h
Postop IBW: 0,125 mg/kg bolus; zn 2x herh 15-30min
CI: <18y, IHD, aneurysmata, glaucoom, hyperthyr., psych+, perf. oogletsel, alcohol+, hallucinatie+

Front 9

Clonidine

Back 9

M: 150 μg/ml; 10x
Alg: 75-150μg 10min; max 0,5mg/dag
Sedatie: 1-2μg/kg 10min; 0,25-2 μg/kg/h

Front 10

Ouderen (>70 jaar): aanpassen dosering

Back 10

10-30% reductie bij ouderen

Front 11

Luchtdrukken (atm, kPA, mmHg, H2O)

Back 11

1 atm = 1.01325 bar = 101.3 kPa = 760 mmHg = 1033 cmH2O

Front 12

Sufentanil

Back 12

Dosering: 10ml 5ug/ml; 2x
Ind TCBW: 0,2-0,7g/kg (K 0,1-0,5)
Cont: 0,1-0,2 ug/kg 20-30min; 0,1-2g/kg/h (V=K)
TCI 0,3 ug/ml
EPA: 0.05-0.2μg/kg oplaad; cont 0,05μg/kg/h

Front 13

Fentanyl

Back 13

M: 2ml 50μg/ml; 10-20x
Ind TBW: 2-7μg/kg (K: 1-5μg/kg)
Cont: 1-2μg/kg 20-30min; 2-20μg/kg/h

Front 14

Piritramide

Back 14

M: 2ml 10mg/ml; 10x
>5y 0,1-0,2 mg/kg

Front 15

Pethidine

Back 15

M: 50mg/ml; 10x
D: 25-50mg; beginnen met 12,5mg
(K 0,5-1mg/kg)

Front 16

Remifentanil

Back 16

M: 50ug/ml
Cont IBW: 5-15μg/kg/h (0,1-0,5μg/kg/min)
RSI: 1μg/kg
TCI: 4 ng/ml
Sedatie: 5-10 μg/kg/h

Front 17

Morfine

Back 17

M: 1ml 10mg/ml; 10x
D IBW: 0,1-0,2 mg/kg 4-6u (K 0,1 4-6u)

Front 18

Tramadol

Back 18

D: 50-100mg 3-5dd IV/PO
K>1: oplaad 2mg/kg; onderh 1-2mg/kg 4dd (max 12mg/kg/dag)

Front 19

Naloxon

Back 19

M: 1ml 0,4mg/ml; 10x
D: 0,1-0,4mg max 1 mg (K 1-10μg/kg)

Front 20

Ibuprofen

Back 20

D: 1200mg 3-4dd, evt 1600mg
K>3m-12y: 20-30mg/kg/dag 3-4dd max 3 dagen

Front 21

Paracetamol

Back 21

D: 0.5-1g 4dd
K >1m: IV opl 20mg/kg max 60 mg/kg/dag; PO 90 mg/kg/dag; sup opl 40mg/kg max. 90 mg/kg/dag

Front 22

Diclofenac

Back 22

M: 3 ml 25mg/ml; 100ml
D: 1mg/kg IV, 50mg 2-3dd PO, max. 150mg/dag (K 1-3mg/kg/dag 2-4dd PO/sup)
Ampul: 25mg/ml; 3ml in 100ml NaCl langzaam
CI: Ulcus, colitis/crohn, beenmergdep., CVD/IHD, NFx/LFx

Front 23

Metamizol

Back 23

M: 2ml 500mg/ml; 100ml
D: 1gr 4dd; 3gr/dag (K>6m 10-12mg/kg max 20mg/kg; 1-3 mg/kg/dag)
CI: Zwanger, NFx, porfyrie, G6PD, beenmergdep.

Front 24

Opioïden verhouding

Back 24

100 μg fentanyl = 10 μg sufentanil = 10 mg morfine = 15 mg piritramide = 100mg tramadol

Front 25

Rocuronium

Back 25

M: 5ml 10mg/ml
D IBW: 0,6mg/kg; RSI: 1mg/kg
Intra-op: 0,1-0,2 mg/kg 30m o.g.v. TOF
Duur 30-45 min.

Front 26

Cisatracurium

Back 26

M: 5ml 2mg/ml
D TBW: 0,15-0,3mg/kg; 3-6μg/kg/min
Duur 20-30 min. Gebruik bij NFx

Front 27

Mivacurium

Back 27

M: 10ml 2 mg/ml
DTBW: 0,2mg/kg; 5-6μg/kg/min
Duur 12-20 min.

Front 28

Atracurium

Back 28

M: 10 mg/ml
DTBW: 0,5mg/kg; 6-8μg/kg/min
Duur 20-30 min. Gebruik bij NFx

Front 29

Succinylcholine

Back 29

M: 2ml 50mg/ml;5x
D TBW: 1mg/kg (K 1-2mg/kg)

Front 30

Neostigmine

Back 30

M: 5ml 0,5mg/ml
D TBW: 25-70μg/kg (max 5mg) K: 0,01mg/kg
+ 1 atropine

Front 31

Sugammadex

Back 31

M: 2/5ml 100mg/ml
D: volledig 16 mg/kg; TOF>2 2mg/kg; TOF<2 4mg/kg

Front 32

Dantroleen

Back 32

M: 0,33mg/ml; 60ml
D: 2-2,5mg/kg à 15min (max 10mg/kg)
20 mg in 60 ml steriel water 40 graden Celsius

Front 33

Ondansetron

Back 33

M: 2ml 2mg/ml
D: 2-3dd 4mg (K 0,1mg/kg)

5-HT3 receptor antagonist (QT!)

Front 34

Droperidol

Back 34

M: 1ml 2,5mg/ml; 1:1
D: 0,625-1,25mg (K 0,02-0,05mg/kg max 1,25 mg)
Dopamine/ α1 antagonist (QT!)

Front 35

Dexamethason

Back 35

M: 1ml 5mg/ml
D: 4-5mg (K 0,15 mg/kg max 5mg 1dd)

Front 36

Metoclopramide

Back 36

M: 2ml 5mg/ml
D: 0,5mg/kg (10mg, max 3dd) (K 0,1-0,15mg/kg max 3dd, max 0,5mg/kg/dag)
D2 + 5-HT3 + 5-HT4 R-antagonist

Front 37

Haloperidol

Back 37

M: 1ml 5mg/ml
D: 0.01mg/kg (max 2.5mg/do)
Dopamine/ α1 antagonist (QT!)

Front 38

Ranitidine

Back 38

M: 2ml 25mg/ml
D: 150mg PO 2dd
RSI: 50mg IV 1-2u vtv.

Front 39

Efedrine

Back 39

M: 1ml 50mg/ml; 10x
D: 0,1mg/kg naar effect

Front 40

Fenylefrine

Back 40

M: 10ml 1mg/ml; 5-10x
D: 50-200μg (K 20μg/kg); 0,1-10μg/kg/min

Front 41

Atropinesulfaat

Back 41

M: 0,5 mg/ml
D: 0,25-0,5mg (K 10μg/kg)

Front 42

Noradrenaline

Back 42

M: 1/5ml 1mg/ml
D: 0,05-2μg/kg/min

Front 43

Dobutamine

Back 43

M: 5mg/ml
D: 1-20μg/kg/min

Front 44

Dopamine

Back 44

M: 5ml 40mg/ml; 10x
D: 1-20μg/kg/min

Front 45

Adrenaline

Back 45

M: 1ml 1mg/ml; 10x
D: 0,01-0,1mg (K 1μg/kg) ;0,01-1μg/kg/min
Reanimatie: 1mg (K 10μg/kg)
Anafylaxie: 0,3-0,5 IM; 2-10μg/min (K 10μg/kg IM; 0,1-1μg/kg/min

Front 46

Milrinone

Back 46

M: 10ml 1mg/ml; 5x
Oplaad: 50μg/kg in 10 min
Continu: 0,3-0,7μg/kg/min
PDE-remmer, ino+, chrono+, dromo+, HMV↑, wedge↓, SVR↓, gelijke O2 consumptie

Front 47

Isoprenaline

Back 47

M: 1ml 1mg/ml; 10x
D: 0,01-1,5μg/kg/min

Front 48

1 𝑔𝑎𝑚𝑚𝑎

Back 48

𝐺𝑒𝑤𝑖𝑐ℎ𝑡 x 3

𝐴𝑎𝑛𝑡𝑎𝑙 𝑚𝑔 𝑖𝑛 50𝑚𝑙

Front 49

α, β - receptoren

Back 49

α1: Perifere vasoconstrictie, hyperglycemie Vasodilatatie, tromb. agg.,
α2: sedatie, analgesie HF↑ (chrono+), prikkelgeleiding↑(dromo+),
β1: contractiliteit↑(ino+), hyperglycemie, lipolyse Perifere vasodilatatie
β2: contractiliteit↑(ino+), hyperglycemie, lipolyse Perifere vasodilatatie, bronchodilatatie, glycolyse↑

Front 50

Inotropica

Back 50

α, β-effect kennen!

Efedrine: + endogene release
Fenylefrine: Reflexbrady, hypoperf.
Noradrenaline: Nierperfusie ↓
Dopamine N/H: Natriurese, 25% tach/AF
Afterload↑
Dobutamine: Weinig tensieverschil
Isoprenaline: HF↑, SV↑ & SVR↓

Front 51

Lidocaïne

Back 51

M: 1% of 2%
Anti-aritmicum: 1-1,5mg/kg; 0,5-1,5mg/kg/h
Viscerale pijn: 0,5mg/kg/h
Inductie: 0,5-1,5mg/kg
Hoestprikkel: 0,5-1mg (5-10 min voor detubatie)

Front 52

Prilocaïne

Back 52

M: 1% of 2%
Spinaal: 40-60mg (max 80mg)

Front 53

Bupivacaine

Back 53

M: 0,25 ; 0,5 ; 0,75%
Spinaal: 10-15mg (0,5%)
Epi: 1-2ml/seg (0,25-0,5%), post-op 0,5-2ml/h/seg (0,125-0,25%) Verlosk: oplaad 0,1-0,125% 8-12ml + 5-10 μg sufentanil

Front 54

Ropivacaine

Back 54

M: 0,2; 0,75; 1%
Epi: 1-2ml/seg (0,5-0,75%); post-op 0,5-2ml/seg/h (0.2%)

Front 55

Toxiciteit locoregionale anesthetica

Back 55

Lidocaïne: Volwassen 4 mg/kg; + Adrenaline 7 mg/kg (max. 300mg)
Prilocaïne: Regionaal 7mg/kg (max. 600mg); spinaal max. 80mg
Bupivacaïne: Volwassen 2mg/kg, 175mg/do, max. 400mg/dag). K, continu max. 0,25-0,4 mg/kg/h
Ropivacaïne: Volwassen 3mg/kg, 300mg/do, 700mg/dag. K 3mg/kg, continu max. 0,3-0,5 mg/kg/h

Front 56

Intralipid

Back 56

M: 20%
D: 1,5 ml/kg in 1min; 2x herh 3-5min; continu 0,25 ml/kg/min. Max 8ml/kg. Bij hypoensie 0,5 ml/kg/min

Front 57

Kalium

Back 57

D: 7.45% (20ml 1mmol/ml)
Op pomp of in zak NaCl/Glucose 5%

Front 58

CaCl

Back 58

M: 10ml 100mg/ml
Aritmie, hypermagn., hypoCa: 500-1000mg in 5-10 min
Ca2+-inhib overdosis: 1-2 g in 10-20 min
10ml = 2.25mmol Ca2+

Front 59

Magnesium

Back 59

M: 5ml 150mg/ml
Pijn: 30-50 mg/kg
Aritmie/astma: 25-50 mg/kg (K 25mg/kg)

Front 60

Furosemide

Back 60

M: 2ml 10 mg/ml
D: 0,1-3 mg/kg IV 1-4 dd (K 1-2mg/kg 1-2dd; max 4mg/kg/do)
Continu: 0,1-1mg/kg/h

Front 61

Metoprolol

Back 61

M: 5ml 1mg/ml
D: 2-5mg IV, zn herh (K 0,1mg/kg; max 0,3mg/kg; continu 1-5μg/kg/min)
Antagonist: Glucagon 1-2mg, (K 20-30μg/kg; max 1mg)

Front 62

Esmolol

Back 62

D: 0,25-0,5 mg/kg IV (V=K)
Cont: 50 μg/kg/min, titreren naar effect

Front 63

Labetalol

Back 63

D: 50mg in 5min IV (K 1-2 mg/kg)
Cont: 0,25-2 mg/kg/h (K 0,2-3), titreren naar effect

Front 64

Urapidil

Back 64

D: 10-15 mg IV z.n. à 5 min max. 100 mg
Cont: 0,1-0,5 mg/kg/h

Front 65

Nitroglyerine

Back 65

M: 5ml 1mg/ml; 10x
D: 0,2-1μg/kg/min (spray 0,4 mg)
Ischemie: 50-100 μg IV + 0,2-1 μg/kg/min
NO; Veneuze & coronaire dilatatie/ isch. perfusie↑, hoge dosis art. vasodilatatie

Front 66

Nitropusside

Back 66

D: 0,5-10 μg/kg/min
NO; gemengd veneus & arterieel; reflextachycardie

Front 67

Ketanserine

Back 67

D: eenmalig 5-10mg
continu: 0,025-0,15 mg/kg/uur
5HT2-a + α1 blokker. Gemengd veneus & arterieel effect

Front 68

Salbutamol IV

Back 68

M: 1ml 0,5 mg/ml; 2x
D: 5-10μg/kg IV (K 5μg/kg) in 10 min
Continu: 0,1-5μg/kg/min

Front 69

Salbutamol inh

Back 69

M: 100g/do
D: 200-400 μg, max 4dd (K 100-200μg, max 8dd)

Front 70

Heparine

Back 70

Puur of 10ml in 500ml NaCl
5ml 5.000IE/ml of 10ml 50IE/ml

Front 71

Clemastine

Back 71

M: 2ml 1mg/ml
D: 2mg, zn herh 15 min
(K 0,025mg/kg/do, max 2dd)

Front 72

Actrapid

Back 72

M: 10ml 100IE/ml; 100x

Front 73

Glucagon

Back 73

D: 1-2mg (K 20-30g/kg max 1mg)
Bij β-blokker intoxicatie

Front 74

Hydrocortison

Back 74

M: 100mg; 2x
D: 1-5mg/kg IV, onderhoud 0,5-2mg/kg 3-4dd
Ampul: 100mg oplossen in 2ml water

Front 75

Tranexaminezuur

Back 75

M: 100mg/ml
Profylaxe: 1000mg
Fibrinolyse: 10-15mg/kg 3-4dd of continu 1-5mg/kg/h

Front 76

Steroïden omrekenen

Back 76

20mg hydrocortison = 5mg prednisolone = 0.75mg dexamethason

Front 77

Cefazoline

Back 77

M: 1gr in 10-20 H2O
D: 1000mg (>80kg 2gr) K<1w/<2kg: 50mg/kg/dag in 2 doses/dag
K<1w/>2kg: 100mg/kg/dag in 2 doses/dag
1-4w: 150mg/kg/dag in 3 do/dag
1mo-18y: 30mg/kg/do eenmalig, >4u herhalen (OK <3u= 1gr; >3u=2gr)

Front 78

Cefuroxim

Back 78

M: 750mg in 20ml
D: 1500mg, herh 750mg 3dd
K 1mo-18y: 50mg/kg/do max 1,5gr, herh 50mg/kg/do 3dd

Front 79

Amoxicilline/Clavulaanzuur

Back 79

D >40kg:

<1u 1000/200mg;

>2u 1000/100, 1000/200 of 2000/200 herh 1000/100 of 1000/200 4dd

1200mg in 20ml water

Front 80

Clindamycine

Back 80

M: 150mg/ml
D: 600mg in 20min, >8u herh
K 1mo-18y <60kg: 10mg/kg/do >8u herh
K >60kg: 600mg/do, obesitas 900mg/do

Front 81

Anafylaxie: adrenaline

Back 81

D: 0,3-0,5 mg I.M. z.n. 5-15 min herh.
Continu 5mg/50ml (100μg/ml) 2-10 μg/min (=1-6 ml/u)
Collaps: 0,1-0,5 mg IV
K: 10 μg/kg I.M. z.n. 5-15 min herh.
Continu: 0,1-1 μg/kg/min
<20kg: 3mg/50ml (60μg/ml) 0,1-1 ml/kg/u
20-50kg: 10mg/50ml (200μg/ml) 0,03-0,3 ml/kg/u

5mg vernevelen

Front 82

Anafylaxie: overig

Back 82

Clemastine (2ml 1mg/ml)
D: 2mg, z.n. herh 15 min
K: 0,025mg/kg/do, max 2dd

Hydrocortison
K: 2mg/kg

Dexamethason
K: 1mg/kg

Front 83

Epiduraal verloskamer

Back 83

IC: ↑ Oxy, ↑ duur, ↑ kunstverl, ↑ hypotensie, ↑ urineret., ↑ motor bl., X ↑ op SC
Oplaad: bupi 1-1,25 mg/ml 8-12 ml + 5-10 μg sufentanil (2ml bupi 0,5% 5x of 4x verdunnen)
PCEA: 5ml, 5ml/u, 10min, 30ml/2u
Doorbraak: 10-15 ml bupi 0,1% (5ml/5min) evt 5 μg sufentanil
Pomp opl.: Bupi 0,1% + sufenta 0,2 μg/ml (10 ml bupi 0,5% + 10 μg sufentanil + 38 NaCl 0.9%)

Front 84

BLS/ALS

Back 84

Shockbaar: 200J (K 4J/kg) elke 4 min adrenaline 1mg (na 3x shock) + 300mg amiodarone (evt 150 na 4 min)
Niet shockbaar: elke 4 min adrenaline 1mg (z.s.m.)
Witnessed arrest: 3x defib --> 300mg amiodarone (150 na 4 min) + adrenaline na 4 min
Thermie, Kalium, Volume, Hypoxie
Toxisch, Tamponade, Tension pneu, Trombo-embolic

Front 85

Tachycardie

Back 85

Shock, CHF, M ischemie, syncope: 3x Synchr DC shock --> 300mg Amiodarone 10-20 min & repeat shock
Narrow reg (AVNRT/Afl): 6 + 12 + 12 Adenosine
Narrow irreg (AF/Afl): B-b/diltiazem; CHF --> digoxine/amiodarone
Broad reg (VT/SVT+BTB): Amiodarone 300mg + 900/24u
Broad irreg (AF+BTB/Torsade): HELP + Magnesium 2gr/10min

Front 86

Bradycardie

Back 86

Asystole risk (recent, Mobitz II, breed QRS, Pauze > 3s)
Atropine 0,5 mg I.V. 6x herh
Isoprenaline 5 μg/min
Adrenaline 2-10 μg/min
Transcutane pacing

Front 87

Hyperkaliëmie

Back 87

- 10 ml 10% CaCl in 5-10min
- 30 ml 10% Cagluconaat in 5-10 min
- 25g glucose met 10EH insuline (50 ml 50%)
- Salbutamol 10-20mg vernevelen
- Dialyse