Gould's Pathophysiology - Chapter 8

Front 1

No blood vessels in the

Back 1

Epidermis

Front 2

Stratum basale, located on

Back 2

Basement membrane

Front 3

New squamous epithelial cells form

Back 3

By mitosis in the stratum basale, only layer of epidermis where mitosis occurs

Front 4

Stratum levels: (B, S, G, L, C)

Back 4

Basale, spinosum, granulosum, lucidum, corneum

Front 5

Recessive trait leading to lack of melanin production

Back 5

Albinism

Front 6

Small areas of hypopigmentation which may gradually spread to involve larger areas

Back 6

Vitiligo

Front 7

Patches of darker skin, often on face, may develop during pregnancy

Back 7

Melasma or chloasma

Front 8

Thick layer of connect tissue that includes elastic and collagen fibers

Back 8

Dermis

Front 9

Urticaria (hives) result from

Back 9

Type I hypersensitivity reaction

Front 10

Eczema

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Atopic dermatitis

Front 11

Atopic refers to

Back 11

Inherited tendency toward allergic conditions

Front 12

Eosinophilia and increased serum IgE levels indicate the allergenic basis for

Back 12

Atopic dematitis

Front 13

Atopic dematitis, increased serum (blank) levels

Back 13

IgE

Front 14

Chronic inflammatory skin disorder, considered to be genetic in origin

Back 14

Psoriasis

Front 15

Abnormal activation of T cells and associated increase in cytokines in affected tissues

Back 15

Psoriasis

Front 16

Glucocortoioids, tar preparations, antimetabolite methotrexate - treatments for

Back 16

Psoriasis

Front 17

Autoimmune skin disorder that comes in several forms:

Back 17

Pemphigus

Front 18

Types of pemphigus:

Back 18

Vulgaris (most common), foliaceus, erythematosus

Front 19

Epidermis separates above basal layer

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Pemphigus vulgaris

Front 20

Eryipelas

Back 20

Cellulitis

Front 21

Cellulitis, usually caused by

Back 21

Staphylococcus aureus

Front 22

Boil (furuncle) usually causes by

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S. aureus

Front 23

Collection of furuncles

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Carbuncle

Front 24

Group A, beta hemolytic Streptococcus (S. pyogenes, also responsible for strep throat)

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Acute necrotizing fascitis

Front 25

Mycobacterium leprae

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Leprosy (Hansens disease)

Front 26

HPV 6 and 11

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Genital warts

Front 27

HPV 1 through 4

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Common plantar warts

Front 28

Mycoses

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Fungal infections

Front 29

Tinea

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Dermaphytoses or ringworm

Front 30

Tinea capitis

Back 30

Scalp infection, microsporum canis or trichophyton tonsurans

Front 31

Fungal infection of body, particular non-hairy parts

Back 31

Tinea corporis

Front 32

Trichophyton mentagrophytes, trichophyton rubrum

Back 32

Tinea pedis, athlete's foot

Front 33

Tinea unguium

Back 33

onychomycosis, infection in nails

Front 34

Results from proliferation of basal cells

Back 34

Seborrheic ketatoses

Front 35

Skin exposes to ultraviolet radiation, commonly arise in fair-skinned persons

Back 35

Actinic keratoses

Front 36

Painless, malignant tumor of epidermis

Back 36

Squamous cell carcinoma

Front 37

Arise from melanocytes in basal layer of epidermis, or from nevus (mole), grows quickly and metastasizes early

Back 37

Malignant melanoma

Front 38

Forms part of etiology of Kaposis sarcoma

Back 38

Herpesvirus #8 (kSHV)

Front 39

Variola

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Smallpox

Front 40

Diagnosis isbased on a blood test, PCR or polymerase chain-reaction, andsymptoms.

Back 40

Lyme disease

Front 41

Seborrheic keratosis,actinic keratosis and nevi (moles).

Back 41

Benign skin tumors

Front 42

Arises from basal cell layer ofepidermis or hair follicles, are locally invasive, but very rarelymetastasize.

Back 42

Basal cell cancer

Front 43

Arises from the epidermis and produces keratin.

Back 43

Squamous cell carcinoma

Front 44

It is more serious than basalcell because of its tendency to metastasize

Back 44

Squamous cell carcinoma

Front 45

A smooth, small, waxynodule that appears translucent.

Back 45

Basal cell carcinoma

Front 46

Characterized by a firm, red nodule with visible scales

Back 46

Squamous cell carcinoma

Front 47

A neoplasm composed ofabnormal melanocytes appearing in both the epidermis anddermis.

Back 47

Malignant Melanoma