Goljan Images 4Of4

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. Granuloma annulare.

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. Acanthosis nigricans

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.Solar lentigo

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. Seborrheic keratosis on the breast

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. Compound nevus

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.Lentigo maligna melanoma

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.Anencephaly

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. Neurofibromatosis

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.Epidural hematoma

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.Subdural hematoma

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.Atherosclerotic stroke.

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.Embolic stroke

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. Intracerebral hemorrhage

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.Bacterial meningitis

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. Cerebral abscess

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.Fusion of the podocytes. Arrowheads show fusion of the podocytes, which should be separated by slit pores. This finding occurs in all glomerular diseases that present with the nephrotic syndrome (e.g., minimal change

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.Gram stain of Streptococcus pneumoniae. The sputum stain shows numerous lancet-shaped diplococci

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.Granular immunofluorescence. Granular irregular deposits in the capillaries are caused by immunocomplex deposition (e.g., poststreptococcal glomerulonephritis

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. brain of a newborn with kernicterus. Arrows depict yellow bilirubin pigment deposited in the basal ganglia

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.Herpes zoster

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.Huntington disease. Coronal section (A) shows a dilated lateral ventricle and atrophy of the caudate, putamen, and globus pallidus when compared with a normal coronal section (B)

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.If the crystal is blue when parallel to the slow ray, the crystal demonstrates positive birefringence.

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.Normal peripheral blood smear showing RBCs. The RBCs are uniform in size, and the central areas of pallor are slightly less than half the total diameter of an RBC. The four dark objects (arrows) outside

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. Giardia lamblia with two nuclei

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. Man with ankylosing spondylitis

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.Keratoacanthoma

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classic Reed-Sternberg (RS) cell. The large, multilobed cell with prominent nucleoli is surrounded by a halo of clear nucleoplasm. Classic RS cells are more easily found in mixed-cellularity Hodgkin's lymphoma

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.Linear immunofluorescence. The uninterrupted smooth immunofluorescence along the glomerular basement membrane is caused by deposition of IgG antibodies directed against the membrane (e.g., Goodpasture syndrome)

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.Liver biopsy stained with Prussian blue in a patient with hereditary hemochromatosis

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.Lung biopsy stained with Gomori methenamine-silver showing septated hyphae and fruiting body (inset) of Aspergillus fumigatus

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.Malignant plasma cells in multiple myeloma. The majority of malignant plasma cells show a gray-blue cytoplasm, peripherally located nuclei, and perinuclear clearing

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.Multiple sclerosis showing multiple areas of demyelinated white matter (arrows pointing to brown plaques)

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analgesic nephropathy showing multiple brownish necrotic papillae (arrows)

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.Neonatal respiratory distress syndrome

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.Neurocysticercosis showing multiple cysts between the gray and white matter

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.Optic disk with papilledema showing loss of the disk margin and hard exudates (white streaks

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.Osteoarthritis. Bony protuberances (Heberden's nodes)

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.Patient with myasthenia gravis showing ptosis of the left eye (A) followed by opening of the eye (B) after intravenous injection of Tensilon.

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.Petechiae in idiopathic thrombocytopenic purpura showing pinpoint hemorrhages, a sign of platelet dysfunction

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.Pneumocystis jiroveci pneumonia. This silver-impregnated cytologic smear

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.Poststreptococcal diffuse proliferative glomerulonephritis

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.Potassium hydroxide preparation of skin scrapings showing hyphae and yeasts

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.Prostate cancer metastatic to the vertebral column. Multiple white foci of metastatic prostate cancer produce an osteoblastic response in the bone.

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.Radiograph of a skull showing multiple punched out lytic lesions in multiple myeloma

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.Radiograph showing small bowel obstruction.

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.Saddle embolus occluding the main branches of the pulmonary artery

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.Senile plaque (arrow) shows an eosinophilic center with peripherally located distended neuronal processes (neurites).

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.Silver stain showing Helicobacter pylori organisms.

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.Spongiform encephalopathy in Creutzfeldt-Jakob disease showing classic bubbles and holes of the neuropil cell bodies

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.Subendothelial immunocomplex deposits viewed with electron microscopy.

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.Substantia nigra in a patient with Parkinson disease (A) and a normal individual (B)

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.Tinea capitis due to Trichophyton tonsurans

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.Tinea corporis showing annular lesions with erythematous margins and clear centers

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.subnuclear vacuoles (arrows) containing mucin push the nuclei of the endometrial cells toward the apex of the cell

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Wernicke's encephalopathy showing hemorrhage and discoloration of mamillary bodies and the wall of the third ventricle

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Wilson's disease showing cavitary necrosis of the putamen on both sides of the brain

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cytomegalovirus. The enlarged nuclei of many of the type I pneumocytes contain large inclusions