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11 Cards in this Set

  • Front
  • Back
The first thing the lumen of the esophagus does when it's obstructed is what? What does this mean re: presentation of cancers?
dilates

they will present w/sx later.
What is the most common sx of esophageal cancer?
- does it present with weight loss?
+ what might that indicate?
- Are chest pain, GI bleeding, and SOB freq or infreq?
almost always w/dysphagia
- sometimes
+ metastatic dz
- infreq, but still possible.
Which is more common in the esophagus, adenocarcinoma or SCC? Which has been increasing in freq? Which is the bigger concern internationally?

What ages groups do they occur in?
approx equally common.
Adenocarcinoma
SCC

Both occur in older individuals (ave age of onset app 70 yo)
Tell me whether the following pts are more likely to have adenocarcinoma or SCC of the esophagus:

1. hx of GERD --> Barrett's
2. AA pt from NC
3. white pt from New Jersey
4. Pt w/ hx of toxic ingestion
5. Alcoholic
6. Pt w/ 30 year smoking hx
Adeno
SCC
Adeno
SCC
SCC
SCC
What else is considered on the DDx list for esophageal cancer?
--> includes:
Esophageal strictures
Extrinsic compression of the esophagus (other cancers, aneurysms, etc)
Viral infection of the esophagus
Benign esophageal growths
Erosive esophagitis
How must dx of esophageal cancer be made?
Endoscopy
CT scan, MRI and EUS often used to assess what in pts w/ confirmed esophageal cancer?
the extent of the tumor
Is Adenocarcinoma a distal or proximal condition in the esophagus? why?

SCC?
distal, b/c that's where Barrett's happens.

proximal/medial
What tx offers the best hope for a cure in esophageal cancer tx? Risks?

Is Xrt/Chemo used?
Resection offers best hope for cure
- this is a tough surgery, 30-40% morbidity, 2-5% mortality.

usually palliatively, occasionally curative
- can be adjuvant
Do most esophageal cancers present at a curable stage? Why might prog in these cancers be so especially poor?
no.

Cancer in the esophagus spreads earlier to local structures b/c the esophagus doesn't have a serosa.
leiomyomas
esophageal cysts
fibrovascular polyps
papillomas
granular cell tumors
Lipomas
... all are what?

are most mucosal growths?

What type of imaging can help determine histology?
benign growths in the esophagus

no, submucosal.

EUS